A consensus statement on detection of hippocampal sharp wave ripples and differentiation from other fast oscillations
Decades of rodent research have established the role of hippocampal sharp wave ripples
(SPW-Rs) in consolidating and guiding experience. More recently, intracranial recordings in …
(SPW-Rs) in consolidating and guiding experience. More recently, intracranial recordings in …
Large-scale neural recordings with single neuron resolution using Neuropixels probes in human cortex
Recent advances in multi-electrode array technology have made it possible to monitor large
neuronal ensembles at cellular resolution in animal models. In humans, however, current …
neuronal ensembles at cellular resolution in animal models. In humans, however, current …
[HTML][HTML] A review of signal processing and machine learning techniques for interictal epileptiform discharge detection
Brain interictal epileptiform discharges (IEDs), as one of the hallmarks of epileptic brain, are
transient events captured by electroencephalogram (EEG). IEDs are generated by seizure …
transient events captured by electroencephalogram (EEG). IEDs are generated by seizure …
Closed-loop enhancement and neural decoding of cognitive control in humans
Deficits in cognitive control—that is, in the ability to withhold a default pre-potent response in
favour of a more adaptive choice—are common in depression, anxiety, addiction and other …
favour of a more adaptive choice—are common in depression, anxiety, addiction and other …
Human brain mapping with multithousand-channel PtNRGrids resolves spatiotemporal dynamics
Y Tchoe, AM Bourhis, DR Cleary, B Stedelin… - Science translational …, 2022 - science.org
Electrophysiological devices are critical for mapping eloquent and diseased brain regions
and for therapeutic neuromodulation in clinical settings and are extensively used for …
and for therapeutic neuromodulation in clinical settings and are extensively used for …
Theta oscillations synchronize human medial prefrontal cortex and amygdala during fear learning
S Chen, Z Tan, W Xia, CA Gomes, X Zhang, W Zhou… - Science …, 2021 - science.org
Numerous animal studies have demonstrated that fear acquisition and expression rely on
the coordinated activity of medial prefrontal cortex (mPFC) and amygdala and that theta …
the coordinated activity of medial prefrontal cortex (mPFC) and amygdala and that theta …
A subpopulation of spikes predicts successful epilepsy surgery outcome
Objective Epileptic spikes are the traditional interictal electroencephalographic (EEG)
biomarker for epilepsy. Given their low specificity for identifying the epileptogenic zone (EZ) …
biomarker for epilepsy. Given their low specificity for identifying the epileptogenic zone (EZ) …
A unifying principle underlying the extracellular field potential spectral responses in the human cortex
E Podvalny, N Noy, M Harel, S Bickel… - Journal of …, 2015 - journals.physiology.org
Electrophysiological mass potentials show complex spectral changes upon neuronal
activation. However, it is unknown to what extent these complex band-limited changes are …
activation. However, it is unknown to what extent these complex band-limited changes are …
Interictal epileptiform activity outside the seizure onset zone impacts cognition
Abstract See Kleen and Kirsch (doi: 10.1093/awx178) for a scientific commentary on this
article. Cognitive deficits are common among epilepsy patients. In these patients, interictal …
article. Cognitive deficits are common among epilepsy patients. In these patients, interictal …
Thalamic deep brain stimulation modulates cycles of seizure risk in epilepsy
Chronic brain recordings suggest that seizure risk is not uniform, but rather varies
systematically relative to daily (circadian) and multiday (multidien) cycles. Here, one human …
systematically relative to daily (circadian) and multiday (multidien) cycles. Here, one human …