Nanomedicines: current status and future perspectives in aspect of drug delivery and pharmacokinetics
YH Choi, HK Han - Journal of pharmaceutical investigation, 2018 - Springer
Nanomedicines have evolved into various forms including dendrimers, nanocrystals,
emulsions, liposomes, solid lipid nanoparticles, micelles, and polymeric nanoparticles since …
emulsions, liposomes, solid lipid nanoparticles, micelles, and polymeric nanoparticles since …
Nanodrugs: pharmacokinetics and safety
To date, various nanodrug systems have been developed for different routes of
administration, which include dendrimers, nanocrystals, emulsions, liposomes, solid lipid …
administration, which include dendrimers, nanocrystals, emulsions, liposomes, solid lipid …
Exploring the application of micellar drug delivery systems in cancer nanomedicine
Various formulations of polymeric micelles, tiny spherical structures made of polymeric
materials, are currently being investigated in preclinical and clinical settings for their …
materials, are currently being investigated in preclinical and clinical settings for their …
Oral bioavailability enhancement through supersaturation: an update and meta-analysis
Introduction: With the increasing number of poorly water-soluble compounds in drug
discovery pipelines, supersaturating drug delivery systems (SDDS) have attracted increased …
discovery pipelines, supersaturating drug delivery systems (SDDS) have attracted increased …
Production of hydrochlorothiazide nanoparticles with increased permeability using top-spray coating process
Hydrochlorothiazide is a diuretic drug and belongs to Biopharmaceutical Classification
System class IV, having poor water solubility and low permeability, thus proportionally …
System class IV, having poor water solubility and low permeability, thus proportionally …
Preparation and characterization of solid dispersion using a novel amphiphilic copolymer to enhance dissolution and oral bioavailability of sorafenib
The objective of the current study was to enhance dissolution and oral bioavailability of the
poorly water-soluble drug, sorafenib (SFN), by solid dispersion (SD) technique using a novel …
poorly water-soluble drug, sorafenib (SFN), by solid dispersion (SD) technique using a novel …
Self-nanomicellizing solid dispersion: A promising platform for oral drug delivery
W Chen, A Yan, T Sun, X Wang, W Sun… - Colloids and Surfaces B …, 2024 - Elsevier
Amorphous solid dispersion (ASD) has been widely used to enhance the oral bioavailability
of water-insoluble drugs for oral delivery because of its advantages of enhancing solubility …
of water-insoluble drugs for oral delivery because of its advantages of enhancing solubility …
The efficiency and mechanism of N-octyl-O, N-carboxymethyl chitosan-based micelles to enhance the oral absorption of silybin
T Yin, Y Zhang, Y Liu, Q Chen, Y Fu, J Liang… - International Journal of …, 2018 - Elsevier
This study demonstrates the preparation of a silybin-loaded N-octyl-O, N-carboxymethyl
chitosan micelle (OCC-SLB) to enhance the oral absorption efficiency of silybin (SLB) and …
chitosan micelle (OCC-SLB) to enhance the oral absorption efficiency of silybin (SLB) and …
Self-micellizing solid dispersion of cyclosporine A with improved dissolution and oral bioavailability
S Onoue, H Suzuki, Y Kojo, S Matsunaga… - European Journal of …, 2014 - Elsevier
The present study aimed to develop a self-micellizing solid dispersion (SMSD) of
cyclosporine A (CsA) using an amphiphilic block copolymer, poly [MPC-co-BMA], to improve …
cyclosporine A (CsA) using an amphiphilic block copolymer, poly [MPC-co-BMA], to improve …
Water-soluble and amphiphilic phospholipid copolymers having 2-methacryloyloxyethyl phosphorylcholine units for the solubilization of bioactive compounds
K Ishihara, M Mu, T Konno - Journal of Biomaterials Science …, 2018 - Taylor & Francis
We summarize the development and evaluation of new type of phospholipid polymers as a
solubilizer for poorly water-soluble compounds. That is, a water-soluble and amphiphilic …
solubilizer for poorly water-soluble compounds. That is, a water-soluble and amphiphilic …