The interest of the scientific community on sex and gender differences in health and disease
has increased substantially over the past 25 to 30 y as a result of a long process of events …

Chronic pain is one of the most debilitating human diseases and represents a social and
economic burden for our society. Great efforts are being made to understand the molecular …

TRPA1 and TRPM8 are transient receptor potential channels expressed in trigeminal
neurons that are related to pathophysiology in migraine models. Here we use a mouse …

The musculoskeletal orofacial pain is a complex symptom of Parkinson's disease (PD)
resulting in stomatognathic system dysfunctions aggravated by the disease rigidity and …

Chronic widespread pain conditions are more prevalent in women than men, suggesting a
role for gonadal hormones in the observed differences. Previously, we showed that female …

Chronic stress produces maladaptive pain responses, manifested as alterations in pain
processing and exacerbation of chronic pain conditions including irritable bowel syndrome …

Resistance training–based exercise is commonly prescribed in the clinic for the treatment of
chronic pain. Mechanisms of aerobic exercise for analgesia are frequently studied, while …

Pain perception is influenced by sex and aging, with previous studies indicating the
involvement of aromatase, the estradiol synthase enzyme, in regulating pain perception …

The present study investigated the efficacy of 6 months of testosterone replacement therapy
(TRT) on chronic pain syndrome in late‐onset hypogonadal (LOH) men. Sixty hypogonadal …

Objective The objective of the study was to assess the differences in dentoskeletal
morphology in males with and without temporomandibular joint osteoarthrosis (TMJOA) …