Lipid droplets are dynamic organelles that store neutral lipids, serve the metabolic needs of
cells, and sequester lipids to prevent lipotoxicity and membrane damage. Here we review …

Perilipins are abundant lipid droplet (LD) proteins present in all metazoans and also in
Amoebozoa and fungi. Humans express five perilipins, which share a similar domain …

Lipophagy is a type of selective autophagy that targets lipid droplets for degradation. Since
the discovery of lipophagy in 2009, research has uncovered a central role for this process in …

Lipid droplets (LDs) are organelles critical for energy storage and membrane lipid
homeostasis, whose number and size are carefully regulated in response to cellular …

Cells respond to lysosomal membrane permeabilization by membrane repair or selective
macroautophagy of damaged lysosomes, termed lysophagy, but it is not fully understood …

Lipid droplets (LDs) are major lipid storage organelles, sequestering energy-rich
triglycerides and serving as nutrient sinks for cellular homeostasis. Observed for over a …

To study the collaboration between lipid droplets (LDs) and lysosomes, and the lipid change
in nonalcoholic fatty liver disease (NAFLD), herein two pH-triggered hydrophility-adjustable …

Lipid droplets (LDs) store lipids that can be utilized during times of scarcity via autophagic
and lysosomal pathways, but how LDs and autophagosomes interact remained unclear …

Lipid droplets (LDs) play a crucial role in maintaining cellular lipid balance by storing and
delivering lipids as needed. However, the intricate lipolytic pathways involved in LD turnover …

Background Nonalcoholic fatty liver disease (NAFLD) has become the most common
chronic liver disease worldwide, whereas there is no approved drug therapy for it due to its …