[HTML][HTML] Partners in leaky gut syndrome: intestinal dysbiosis and autoimmunity

Y Kinashi, K Hase - Frontiers in immunology, 2021 - frontiersin.org
The intestinal surface is constitutively exposed to diverse antigens, such as food antigens,
food-borne pathogens, and commensal microbes. Intestinal epithelial cells have developed …

Role of the gut microbiome in three major psychiatric disorders

J Borkent, M Ioannou, JD Laman… - Psychological …, 2022 - cambridge.org
Major depressive disorder (MDD), bipolar disorder (BD) and schizophrenia-spectrum
disorders (SSD) are heterogeneous psychiatric disorders, which place significant burden on …

[HTML][HTML] An open label, non-randomized study assessing a prebiotic fiber intervention in a small cohort of Parkinson's disease participants

DA Hall, RM Voigt, TM Cantu-Jungles… - Nature …, 2023 - nature.com
A pro-inflammatory intestinal microbiome is characteristic of Parkinson's disease (PD).
Prebiotic fibers change the microbiome and this study sought to understand the utility of …

Biomarkers for assessment of intestinal permeability in clinical practice

B Seethaler, M Basrai, AM Neyrinck… - American Journal …, 2021 - journals.physiology.org
Intestinal permeability is an important diagnostic marker, yet its determination by established
tests, which measure the urinary excretion of orally administered tracer molecules, is time …

[HTML][HTML] Short-chain fatty acids are key mediators of the favorable effects of the Mediterranean diet on intestinal barrier integrity: data from the randomized controlled …

B Seethaler, NK Nguyen, M Basrai, M Kiechle… - The American journal of …, 2022 - Elsevier
ABSTRACT Background The Mediterranean diet is associated with the prevention of
diabetes, cardiovascular disease, and cancer, all of which are linked to intestinal barrier …

[HTML][HTML] Impaired intestinal barrier and tissue bacteria: pathomechanisms for metabolic diseases

L Massier, M Blüher, P Kovacs… - Frontiers in …, 2021 - frontiersin.org
An intact intestinal barrier, representing the interface between inner and outer environments,
is an integral regulator of health. Among several factors, bacteria and their products have …

[HTML][HTML] Zonulin as a potential therapeutic target in microbiota-gut-brain axis disorders: encouraging results and emerging questions

A Veres-Székely, C Szász, D Pap, B Szebeni… - International journal of …, 2023 - mdpi.com
The relationship between dysbiosis and central nervous diseases has been proved in the
last 10 years. Microbial alterations cause increased intestinal permeability, and the …

[HTML][HTML] Mechanisms of food-induced symptom induction and dietary management in functional dyspepsia

K Duncanson, G Burns, J Pryor, S Keely, NJ Talley - Nutrients, 2021 - mdpi.com
Functional dyspepsia (FD) is a common disorder of gut-brain interaction, characterised by
upper gastrointestinal symptom profiles that differentiate FD from the irritable bowel …

High-altitude exposures and intestinal barrier dysfunction

ZJ McKenna, F Gorini Pereira… - American Journal …, 2022 - journals.physiology.org
Gastrointestinal complaints are often reported during ascents to high altitude (> 2,500 m),
though their etiology is not known. One potential explanation is injury to the intestinal barrier …

Rheumatoid arthritis is associated with increased gut permeability and bacterial translocation that are reversed by inflammation control

R Audo, P Sanchez, B Rivière, J Mielle, J Tan… - …, 2023 - academic.oup.com
Objective To assess how RA and DMARDs affect gut permeability. Methods To explore
colonic mucosa integrity, tight junction proteins zonula occludens-1, occludin and claudin 2 …