Mycobacterium tuberculosis (Mtb), the etiological agent of tuberculosis (TB), is recognized
as a global health emergency as promoted by the World Health Organization. Over 1 million …

The current tuberculosis (TB) predicament poses numerous challenges and therefore every
incremental scientific work and all positive socio-political engagements, are steps taken in …

Mycobacterium tuberculosis' success as a pathogen comes from its ability to evade
degradation by macrophages. Normally macrophages clear microorganisms that activate …

Non-tuberculous mycobacteria (NTM) are paradigmatic colonizers of the total environment,
circulating at the interfaces of the atmosphere, lithosphere, hydrosphere, biosphere, and …

Mycobacteria are well known for their taxonomic diversity, their impact on global health, and
for their atypical cell wall and envelope. In addition to a cytoplasmic membrane and a …

Chemotherapy for tuberculosis (TB) is lengthy and could benefit from synergistic adjuvant
therapeutics that enhance current and novel drug regimens. To identify genetic determinants …

Mycobacterium tuberculosis, the bacterium responsible for tuberculosis, is the global
leading cause of mortality from an infectious agent. Part of this success relies on the unique …

Mycobacterium tuberculosis (Mtb) imports and metabolizes fatty acids to maintain infection
within human macrophages. Although this is a well-established paradigm, the bacterial …

Sacculus is a peptidoglycan (PG) matrix that protects bacteria from osmotic lysis. In Gram-
positive organisms, the sacculus is densely functionalized with glycopolymers important for …

The bacterial cell wall is a complex polymeric structure with essential roles in defence,
survival and pathogenesis. Common to both Gram-positive and Gram-negative bacteria is …