Critically ill patients often acquire neuropathy and/or myopathy labeled ICU-acquired
weakness. The current insights into incidence, pathophysiology, diagnostic tools, risk …

Mechanical ventilation may have adverse effects on both the lung and the diaphragm. Injury
to the lung is mediated by excessive mechanical stress and strain, whereas the diaphragm …

Importance High-flow conditioned oxygen therapy delivered through nasal cannulae and
noninvasive mechanical ventilation (NIV) may reduce the need for reintubation. Among the …

Importance Studies of mechanically ventilated critically ill patients that combine populations
that are at high and low risk for reintubation suggest that conditioned high-flow nasal …

Rationale: Diaphragm atrophy and dysfunction have been reported in humans during
mechanical ventilation, but the prevalence, causes, and functional impact of changes in …

Respiratory muscle ultrasound is used to evaluate the anatomy and function of the
respiratory muscle pump. It is a safe, repeatable, accurate, and non-invasive bedside …

Purpose Ultrasound measurements of diaphragm thickness (T di) and thickening (TF di) may
be useful to monitor diaphragm activity and detect diaphragm atrophy in mechanically …

Purpose Diaphragmatic dysfunction (DD) has a high incidence in critically ill patients and is
an under-recognized cause of respiratory failure and prolonged weaning from mechanical …

We present areas of uncertainty concerning intensive care unit-acquired weakness (ICUAW)
and identify areas for future research. Age, pre-ICU functional and cognitive state …

The diaphragm is the major muscle of inspiration, and its function is critical for optimal
respiration. Diaphragmatic failure has long been recognized as a major contributor to death …