Structure, function, and pharmacology of glutamate receptor ion channels
Many physiologic effects of l-glutamate, the major excitatory neurotransmitter in the
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …
mammalian central nervous system, are mediated via signaling by ionotropic glutamate …
Structure, function, and allosteric modulation of NMDA receptors
NMDA-type glutamate receptors are ligand-gated ion channels that mediate a Ca2+-
permeable component of excitatory neurotransmission in the central nervous system (CNS) …
permeable component of excitatory neurotransmission in the central nervous system (CNS) …
Functional properties of insect olfactory receptors: ionotropic receptors and odorant receptors
D Wicher, F Miazzi - Cell and Tissue Research, 2021 - Springer
The majority of insect olfactory receptors belong to two distinct protein families, the
ionotropic receptors (IRs), which are related to the ionotropic glutamate receptor family, and …
ionotropic receptors (IRs), which are related to the ionotropic glutamate receptor family, and …
The biology and pathobiology of glutamatergic, cholinergic, and dopaminergic signaling in the aging brain
A Gasiorowska, M Wydrych, P Drapich… - Frontiers in aging …, 2021 - frontiersin.org
The elderly population is growing worldwide, with important health and socioeconomic
implications. Clinical and experimental studies on aging have uncovered numerous …
implications. Clinical and experimental studies on aging have uncovered numerous …
MOLEonline: a web-based tool for analyzing channels, tunnels and pores (2018 update)
MOLEonline is an interactive, web-based application for the detection and characterization
of channels (pores and tunnels) within biomacromolecular structures. The updated version …
of channels (pores and tunnels) within biomacromolecular structures. The updated version …
AMPA receptor GluA2 subunit defects are a cause of neurodevelopmental disorders
AMPA receptors (AMPARs) are tetrameric ligand-gated channels made up of combinations
of GluA1-4 subunits encoded by GRIA1-4 genes. GluA2 has an especially important role …
of GluA1-4 subunits encoded by GRIA1-4 genes. GluA2 has an especially important role …
[HTML][HTML] Opening of glutamate receptor channel to subconductance levels
MV Yelshanskaya, DS Patel, CM Kottke, MG Kurnikova… - Nature, 2022 - nature.com
Ionotropic glutamate receptors (iGluRs) are tetrameric ligand-gated ion channels that open
their pores in response to binding of the agonist glutamate,–. An ionic current through a …
their pores in response to binding of the agonist glutamate,–. An ionic current through a …
Merging signaling with structure: functions and mechanisms of plant glutamate receptor ion channels
AA Simon, C Navarro-Retamal… - Annual Review of Plant …, 2023 - annualreviews.org
Plant glutamate receptor-like (GLR) genes encode ion channels with demonstrated roles in
electrical and calcium (Ca2+) signaling. The expansion of the GLR family along the lineage …
electrical and calcium (Ca2+) signaling. The expansion of the GLR family along the lineage …
Opening of the human epithelial calcium channel TRPV6
Calcium-selective transient receptor potential vanilloid subfamily member 6 (TRPV6)
channels play a critical role in calcium uptake in epithelial tissues,,,. Altered TRPV6 …
channels play a critical role in calcium uptake in epithelial tissues,,,. Altered TRPV6 …
Neurodevelopmental disorders associated with PSD-95 and its interaction partners
AM Levy, P Gomez-Puertas, Z Tümer - International Journal of Molecular …, 2022 - mdpi.com
The postsynaptic density (PSD) is a massive protein complex, critical for synaptic strength
and plasticity in excitatory neurons. Here, the scaffolding protein PSD-95 plays a crucial role …
and plasticity in excitatory neurons. Here, the scaffolding protein PSD-95 plays a crucial role …