Leptin, the protein product of the obese (ob or Lep) gene, is a hormone synthesized by
adipocytes that signals available energy reserves to the brain, and thereby influences …

To achieve energy balance and maintain a constant BW, changes in feed intake and energy
expenditure must be coordinated and tightly regulated. This may not hold true for some …

Nutrition has long been considered more the domain of medicine and agriculture than of the
biological sciences, yet it touches and shapes all aspects of the natural world. The need for …

Lipid storage is an evolutionary conserved process that exists in all organisms from simple
prokaryotes to humans. In Metazoa, long-term lipid accumulation is restricted to specialized …

In this sweeping exploration of the relatively recent obesity epidemic, Michael L. Power and
Jay Schulkin probe evolutionary biology, history, physiology, and medical science to …

The production of peptide hormones by skeletal muscle tissue is a promising area of gene
therapy. Skeletal muscle myogenesis can be induced in vitro, resulting in the fusion of …

Leptin is a key factor for the regulation of food intake and energy homeostasis in mammals,
but information regarding its role in teleosts is still limited. There are large differences …

Leptin is an adipocyte-derived hormone/cytokine that links nutritional status with
neuroendocrine and immune functions. Initially described as an anti-obesity hormone, leptin …

The present study reports the complete coding sequences for two paralogues for leptin
(sLepA1 and sLepA2) and leptin receptor (sLepR) in Atlantic salmon. The deduced 171 …

The neuroendocrinology of ingestive behavior is a topic central to human health, particularly
in light of the prevalence of obesity, eating disorders, and diabetes. The study of food intake …