HLA-G is a molecule that was first known to confer protection to the fetus from destruction by
the immune system of its mother, thus critically contributing to fetal–maternal tolerance. The …

The genetic factors associated with susceptibility or resistance to viral infections are likely to
involve a sophisticated array of immune response. These genetic elements may modulate …

The HLA-G gene displays several peculiarities that are distinct from those of classical HLA
class I genes. The unique structure of the HLA-G molecule permits a restricted peptide …

The HLA-C locus is distinct relative to the other classical HLA class I loci in that it has
relatively limited polymorphism, lower expression on the cell surface,, and more extensive …

HLA-G has a relevant role in immune response regulation. The overall structure of the HLA-
G coding region has been maintained during the evolution process, in which most of its …

In human tumors alterations in the surface expression and/or function of the major
histocompatibility complex (MHC) class I antigens are frequently found and equip neoplastic …

HLA-G molecule has well-recognized tolerogenic properties, and the encoding gene shows
lower frequency of polymorphism at the coding region but higher variability at regulatory …

Human leukocyte antigen G (HLA-G) belongs to the family of non-classical HLA class I
genes, located within the major histocompatibility complex (MHC). HLA-G has been the …

HLA-G molecule plays an important role on immune response regulation and has been
implicated on the inhibition of T and natural killer cell cytolytic function and inhibition of …

Background MicroRNAs (miRNAs) are involved in cancer development and progression,
acting as tumor suppressors or oncogenes. Our previous studies have revealed that miR …