From ancient to emerging infections: the odyssey of viruses in the male genital tract

A Le Tortorec, G Matusali, D Mahé… - Physiological …, 2020 - journals.physiology.org
The male genital tract (MGT) is the target of a number of viral infections that can have
deleterious consequences at the individual, offspring, and population levels. These …

The state of latency in microbial pathogenesis

L Pirofski, A Casadevall - The Journal of Clinical …, 2020 - Am Soc Clin Investig
The state of latency occurs when a microbe's persistence in a host produces host damage
without perturbing homeostasis sufficiently to cause clinical symptoms or disease. The …

Two-step fitness selection for intra-host variations in SARS-CoV-2

J Li, P Du, L Yang, J Zhang, C Song, D Chen, Y Song… - Cell reports, 2022 - cell.com
Spontaneous mutations introduce uncertainty into coronavirus disease 2019 (COVID-19)
control procedures and vaccine development. Here, we perform a spatiotemporal analysis …

Atypical prolonged viral shedding with intra-host SARS-CoV-2 evolution in a mildly affected symptomatic patient

MP Cunha, APP Vilela, CV Molina, SM Acuna… - Frontiers in …, 2021 - frontiersin.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is caused by
a respiratory virus with a wide range of manifestations, varying from asymptomatic to fatal …

Electrochemical magneto-immunoassay for detection of zika virus antibody in human serum

KR Castro, GO Setti, TR de Oliveira… - Talanta, 2023 - Elsevier
Zika virus (ZIKV) is a flavivirus transmitted by infected Aedes genus mosquitoes. An infected
person may be asymptomatic or present symptoms such as fever, arthralgia, and in …

Zika Virus Envelope Domain III Recombinant Protein Delivered With Saponin-Based Nanoadjuvant From Quillaja brasiliensis Enhances Anti-Zika Immune …

S Cibulski, APM Varela, TF Teixeira… - Frontiers in …, 2021 - frontiersin.org
Nanoadjuvants that combine immunostimulatory properties and delivery systems reportedly
bestow major improvements on the efficacy of recombinant, protein-based vaccines. Among …

[HTML][HTML] Evidence of Zika virus reinfection by genome diversity and antibody response analysis, Brazil

M da Costa Castilho, AMB de Filippis… - Emerging Infectious …, 2024 - ncbi.nlm.nih.gov
We generated 238 Zika virus (ZIKV) genomes from 135 persons in Brazil who had samples
collected over 1 year to evaluate virus persistence. Phylogenetic inference clustered the …

Safety, tumor reduction, and clinical impact of Zika virus injection in dogs with advanced-stage brain tumors

C Kaid, RA dos Santos Madi, R Astray, E Goulart… - Molecular Therapy, 2020 - cell.com
Malignant brain tumors are among the most aggressive cancers with poor prognosis and no
effective treatment. Recently, we reported the oncolytic potential of Zika virus infecting and …

IMXQB-80: A Quillaja brasiliensis saponin-based nanoadjuvant enhances Zika virus specific immune responses in mice

S Cibulski, TF Teixeira, APM Varela, MF de Lima… - Vaccine, 2021 - Elsevier
Vaccine adjuvants are compounds that enhance/prolong the immune response to a co-
administered antigen. Saponins have been widely used as adjuvants for many years in …

Zika virus exposure affects neuron-glia communication in the hippocampal slices of adult rats

LD Bobermin, A Quincozes-Santos, CL Santos… - Scientific Reports, 2020 - nature.com
Zika virus (ZIKV) infection during pregnancy was associated with microcephaly in neonates,
but clinical and experimental evidence indicate that ZIKV also causes neurological …