Carcinogen-mediated oxidant formation and oxidative DNA damage

K Frenkel - Pharmacology & therapeutics, 1992 - Elsevier
This article reviews the experimental data that points to formation of reactive oxygen species
(ROS) and oxidative DNA base damage as being important contributors to cancer …

Some inferences from in vivo experiments with metal and metal oxide nanoparticles: the pulmonary phagocytosis response, subchronic systemic toxicity and …

BA Katsnelson, LI Privalova… - International Journal …, 2015 - Taylor & Francis
The purpose of this paper is to overview and summarize previously published results of our
experiments on white rats exposed to either a single intratracheal instillation or repeated …

Comparative in Vivo Assessment of Some Adverse Bioeffects of Equidimensional Gold and Silver Nanoparticles and the Attenuation of Nanosilver's Effects with a …

BA Katsnelson, LI Privalova, VB Gurvich… - International journal of …, 2013 - mdpi.com
Stable suspensions of nanogold (NG) and nanosilver (NS) with mean particle diameter 50
and 49 nm, respectively, were prepared by laser ablation of metals in water. To assess rat's …

Toxic effects of low-level long-term inhalation exposures of rats to nickel oxide nanoparticles

MP Sutunkova, SN Solovyeva, IA Minigalieva… - International journal of …, 2019 - mdpi.com
Rats were exposed to nickel oxide nanoparticles (NiO-NP) inhalation at 0.23±0.01 mg/m3
for 4 ha day 5 times a week for up to 10 months. The rat organism responded to this impact …

[PDF][PDF] Пневмокониозы: патогенез и биологическая профилактика

БА Кацнельсон, ОГ Алексеева… - Екатеринбург: УрО …, 1995 - researchgate.net
Пневмокониозы, т. е. заболевания, наиболее характерной чертой которых является
развитие пневмосклероза на почве длительного накопления в легких различных …

On the contribution of the phagocytosis and the solubilization to the iron oxide nanoparticles retention in and elimination from lungs under long-term inhalation …

MP Sutunkova, BA Katsnelson, LI Privalova… - Toxicology, 2016 - Elsevier
The aim of our study was to test a hypothesis according to which the pulmonary clearance
vs. retention of metal oxide nanoparticles (NPs) is controlled not only by physiological …

Experimental research into metallic and metal oxide nanoparticle toxicity in vivo

BA Katsnelson, LI Privalova, MP Sutunkova… - Bioactivity of engineered …, 2017 - Springer
We studied purposefully produced silver, gold, iron oxide, copper oxide, nickel oxide,
manganese oxide, lead oxide, and zinc oxide nanoparticles using two experimental …

Some Peculiarities of Pulmonary Clearance Mechanisms in Rats after Intratracheal Instillation of Magnetite (Fe3O4) Suspensions with Different Particle Sizes in the …

B Katsnelson, LI Privalova, SV Kuzmin… - … of Occupational and …, 2010 - Taylor & Francis
We studied differences between phagocytic responses to nanoparticles (NPs) versus
microparticles in the pulmonary region by synthesizing magnetite of different sizes and …

Kinetics of the bronchoalveolar leucocyte response in rats during exposure to equal airborne mass concentrations of quartz, chrysotile asbestos, or titanium dioxide.

K Donaldson, RE Bolton, A Jones, GM Brown… - Thorax, 1988 - thorax.bmj.com
The kinetics of the bronchoalveolar response was assessed in rats exposed, at equal
airborne mass concentration (10 mg/m3), to titanium dioxide--a non-pathogenic dust--and …

The interaction of inhaled toxicants with respiratory tract clearance mechanisms

RB Schlesinger - Critical reviews in toxicology, 1990 - Taylor & Francis
The internal surfaces of the respiratory tract comprise an extensive interface which is
directly, and continually, exposed to the external environment via inhaled air. Along with …