After asthma: redefining airways diseases
Executive summary Asthma is responsible for considerable global morbidity and health-care
costs. Substantial progress was made against key outcomes such as hospital admissions …
costs. Substantial progress was made against key outcomes such as hospital admissions …
Treatable traits: a new paradigm for 21st century management of chronic airway diseases: Treatable Traits Down Under International Workshop report
“Treatable traits” have been proposed as a new paradigm for the management of airway
diseases, particularly complex disease, which aims to apply personalised medicine to each …
diseases, particularly complex disease, which aims to apply personalised medicine to each …
Treatable traits: toward precision medicine of chronic airway diseases
A Agusti, E Bel, M Thomas… - European …, 2016 - Eur Respiratory Soc
Asthma and chronic obstructive pulmonary disease (COPD) are two prevalent chronic
airway diseases that have a high personal and social impact. They likely represent a …
airway diseases that have a high personal and social impact. They likely represent a …
Identification and validation of distinct biological phenotypes in patients with acute respiratory distress syndrome by cluster analysis
LD Bos, LR Schouten, LA Van Vught, MA Wiewel… - Thorax, 2017 - thorax.bmj.com
Rationale We hypothesised that patients with acute respiratory distress syndrome (ARDS)
can be clustered based on concentrations of plasma biomarkers and that the thereby …
can be clustered based on concentrations of plasma biomarkers and that the thereby …
Precision medicine in airway diseases: moving to clinical practice
On February 21, 2017, a European Respiratory Society research seminar held in Barcelona
discussed how to best apply precision medicine to chronic airway diseases such as asthma …
discussed how to best apply precision medicine to chronic airway diseases such as asthma …
Current concepts in targeting chronic obstructive pulmonary disease pharmacotherapy: making progress towards personalised management
Chronic obstructive pulmonary disease (COPD) is a common, complex, and heterogeneous
disorder that is responsible for substantial and growing morbidity, mortality, and health-care …
disorder that is responsible for substantial and growing morbidity, mortality, and health-care …
Mechanisms of the Development of Allergy (MeDALL): Introducing novel concepts in allergy phenotypes
Asthma, rhinitis, and eczema are complex diseases with multiple genetic and environmental
factors interlinked through IgE-associated and non–IgE-associated mechanisms …
factors interlinked through IgE-associated and non–IgE-associated mechanisms …
Exhaled molecular fingerprinting in diagnosis and monitoring: validating volatile promises
AW Boots, LD Bos, MP van der Schee… - Trends in molecular …, 2015 - cell.com
Medical diagnosis and phenotyping increasingly incorporate information from complex
biological samples. This has promoted the development and clinical application of non …
biological samples. This has promoted the development and clinical application of non …
The asthma–COPD overlap syndrome: towards a revised taxonomy of chronic airways diseases?
Most research of treatments for airways diseases has been restricted to patients who meet
standard definitions of either chronic obstructive pulmonary disease (COPD) or asthma, yet …
standard definitions of either chronic obstructive pulmonary disease (COPD) or asthma, yet …
[HTML][HTML] Chronic Obstructive Pulmonary Disease (COPD) as a disease of early aging: Evidence from the EpiChron Cohort
Background Aging is an important risk factor for most chronic diseases. Patients with COPD
develop more comorbidities than non-COPD subjects. We hypothesized that the …
develop more comorbidities than non-COPD subjects. We hypothesized that the …