The lack of representation of diverse ancestral backgrounds in genomic research is well-
known, and the resultant scientific and ethical limitations are becoming increasingly …

Type 2 diabetes mellitus (T2DM), which was once thought to be rare in sub-Saharan Africa
(SSA), is now well established in this region. The SSA region is undergoing a rapid but …

Hypertension and obesity are the most important modifiable risk factors for cardiovascular
diseases, but their association is not well characterized in Africa. We investigated regional …

Abstract Sub-Saharan Africa (SSA) is the region with the highest projected rates of increase
in type 2 diabetes (129% by 2045), which will exacerbate the already high prevalence of …

Early identification of genetic risk factors for complex diseases can enable timely
interventions and prevent serious outcomes, including mortality. While the genetics …

Abstract Background Type 2 diabetes (T2D) has reached epidemic proportions globally,
including in Africa. However, molecular studies to understand the pathophysiology of T2D …

Low-and middle-income countries (LMIC) constitute the majority of the world's population
and bear more than 80% of the global burden of cardiovascular disease (CVD). 1, 2 The …

Background The targeted application of cutting-edge high-throughput molecular data
technologies provides an enormous opportunity to address key health, economic and …

Developing a complex collaborative program across multiple African countries,
characterized by a diversity of government models, laws, cultures and norms, resources and …

Precision diabetes medicine (PDM) aims to reduce errors in prevention programmes,
diagnosis thresholds, prognosis prediction and treatment strategies. However, its …