[HTML][HTML] The urothelium: a multi-faceted barrier against a harsh environment

NV Jafari, JL Rohn - Mucosal Immunology, 2022 - Elsevier
All mucosal surfaces must deal with the challenge of exposure to the outside world. The
urothelium is a highly specialized layer of stratified epithelial cells lining the inner surface of …

Urine-derived stem cells: applications in regenerative and predictive medicine

G Bento, AK Shafigullina, AA Rizvanov, VA Sardão… - Cells, 2020 - mdpi.com
Despite being a biological waste, human urine contains a small population of cells with self-
renewal capacity and differentiation potential into several cell types. Being derived from the …

Tissue engineering and regenerative medicine in pediatric urology: urethral and urinary bladder reconstruction

M Casarin, A Morlacco, F Dal Moro - International Journal of Molecular …, 2022 - mdpi.com
In the case of pediatric urology there are several congenital conditions, such as
hypospadias and neurogenic bladder, which affect, respectively, the urethra and the urinary …

Tissue engineering for human urethral reconstruction: systematic review of recent literature

V de Kemp, P de Graaf, JO Fledderus… - PloS one, 2015 - journals.plos.org
Background Techniques to treat urethral stricture and hypospadias are restricted, as
substitution of the unhealthy urethra with tissue from other origins (skin, bladder or buccal …

State of the art of clinical applications of tissue engineering in 2021

JL Paternoster, JJ Vranckx - Tissue Engineering Part B: Reviews, 2022 - liebertpub.com
Tissue engineering (TE) was introduced almost 30 years ago as a potential technique for
regenerating human tissues. However, despite promising laboratory findings, the complexity …

Use of alternative techniques and grafts in urethroplasty

BM Browne, AJ Vanni - Urologic Clinics, 2017 - urologic.theclinics.com
The repair of urethral stricture is approached with multiple different techniques, ranging from
endoscopic incision to graft placement for open reconstruction, in an attempt to open and …

Genitourinary tissue engineering: Reconstruction and research models

C Caneparo, D Brownell, S Chabaud, S Bolduc - Bioengineering, 2021 - mdpi.com
Tissue engineering is an emerging field of research that initially aimed to produce 3D
tissues to bypass the lack of adequate tissues for the repair or replacement of deficient …

The potential role of tissue‐engineered urethral substitution: clinical and preclinical studies

A Atala, M Danilevskiy, A Lyundup… - Journal of tissue …, 2017 - Wiley Online Library
Urethral strictures and anomalies remain among the difficult problems in urology, with
urethroplasty procedures being the most effective treatment options. The two major types of …

[HTML][HTML] Tissue engineering graft for urethral reconstruction: is it ready for clinical application?

M Ortac, TO Ekerhult, W Zhao, A Atala - Turkish Journal of Urology, 2023 - ncbi.nlm.nih.gov
Despite developing surgical techniques in urethral surgery, the outcome and complications
are still unsatisfactory. Alternative treatment modality has been coming up, particularly in …

Current status of tissue engineering in the management of severe hypospadias

TO Abbas, E Mahdi, A Hasan, A AlAnsari… - Frontiers in …, 2018 - frontiersin.org
Hypospadias, characterized by misplacement of the urinary meatus in the lower side of the
penis, is a frequent birth defect in male children. Because of the huge variation in the …