[HTML][HTML] Polymer-and lipid-based nanocarriers for ocular drug delivery: current status and future perspectives

H Han, S Li, M Xu, Y Zhong, W Fan, J Xu, T Zhou… - Advanced Drug Delivery …, 2023 - Elsevier
Ocular diseases seriously affect patients' vision and life quality, with a global morbidity of
over 43 million blindness. However, efficient drug delivery to treat ocular diseases …

Overview of recent advances in nano-based ocular drug delivery

LC Liu, YH Chen, DW Lu - International Journal of Molecular Sciences, 2023 - mdpi.com
Ocular diseases profoundly impact patients' vision and overall quality of life globally.
However, effective ocular drug delivery presents formidable challenges within clinical …

Formulation development, optimization, and in vitro assessment of thermoresponsive ophthalmic pluronic F127-chitosan in situ tacrolimus gel

D Modi, Mohammad, MH Warsi, V Garg… - Journal of …, 2021 - Taylor & Francis
To overcome problems associated with topical delivery of tacrolimus (TCS), a
thermoresponsive in situ gel system containing pluronic F127 (PL), and chitosan (CS) was …

Therapeutic approaches for age-related macular degeneration

RM Galindo-Camacho, C Blanco-Llamero… - International journal of …, 2022 - mdpi.com
Damage to the retinal pigment epithelium, Bruch's membrane and/or tissues underlying
macula is known to increase the risk of age-related macular degeneration (AMD). AMD is …

Combination of self-assembling system and N, O-carboxymethyl chitosan improves ocular residence of anti-glaucoma drug

V Kailasam, BN Kumara, KS Prasad, J Nirmal - European Journal of …, 2024 - Elsevier
Glaucoma is known to be one of the principal causes of vision loss due to elevated
intraocular pressure. Currently, latanoprost eye drops is used as first-line treatment for …

Emerging innovations in nano-enabled therapy against age-related macular degeneration: A paradigm shift

SK Dubey, R Pradhan, S Hejmady, G Singhvi… - International Journal of …, 2021 - Elsevier
Age-related macular degeneration (AMD), a degenerative eye disease, is the major cause of
irreversible loss of vision among individuals aged 50 and older. Both genetic and …

Recent Advances in Nanomedicine for Ocular Fundus Neovascularization Disease Management

Y Zhou, M Xu, W Shen, Y Xu, A Shao… - Advanced …, 2024 - Wiley Online Library
As an indispensable part of the human sensory system, visual acuity may be impaired and
even develop into irreversible blindness due to various ocular pathologies. Among ocular …

Self-assembled nanomicellar formulation of docetaxel as a potential breast cancer chemotherapeutic system

M Alshamrani, NJ Ayon, A Alsalhi, O Akinjole - Life, 2022 - mdpi.com
Docetaxel (DTX) is classified as a class IV drug that exhibits poor aqueous solubility (6–7
µg/mL in water) and permeability (P-glycoprotein substrate). The main objective of this study …

Nanotechnology for age-related macular degeneration

B Yang, G Li, J Liu, X Li, S Zhang, F Sun, W Liu - Pharmaceutics, 2021 - mdpi.com
Age-related macular degeneration (AMD) is a degenerative eye disease that is the leading
cause of irreversible vision loss in people 50 years and older. Today, the most common …

Recent advances in novel formulation approaches for tacrolimus delivery in treatment of various ocular diseases

V Kailasam, SS Cheruvu, M Malani… - Journal of Drug Delivery …, 2022 - Elsevier
Tacrolimus, in spite of its good safety profile with fewer adverse effects (when treated locally)
is still being used as an off-label drug to treat ocular diseases-like corneal graft-versus-host …