Cancer testis antigens have been of interest as possible targets for cancer
immunotherapies. To better understand the opportunities for the use of such immunotherapy …

Background: Despite the fact that only modest adaptive immune system related approaches
to treating Alzheimer's disease (AD) are available, an immunogenomics approach to the …

With lung cancer remaining a challenging disease, new approaches to biomarker discovery
and therapy development are needed. Recent immunogenomics, adaptive immune receptor …

Immune-modulating systemic therapies are often used to treat advanced cancer such as
metastatic clear cell renal cell carcinoma (ccRCC). Used alone, sequence-based …

While for certain cancers, such as cervical cancer, the link to viral infections is very strong
and very clear, other cancers represent a history of links to viral infections that are either co …

Overexpression of the secretory protein renalase-1 negatively impacts the survival of
melanoma and pancreatic cancer patients, while inhibition of renalase-1 signaling drives …

The liver is a site of immune privilege, compared with the bladder and skin, for example. To
study this attenuation of the immune response in the cancer setting, we compared quantities …

To better understand how adaptive immune receptors (IRs) in hepatocellular carcinoma
(HCC) microenvironments are related to disease outcomes, we employed a chemical …

PURPOSE In certain cancers, oncogene amplification is correlated with an immunologically
cold or noninflamed, tumor immune microenvironment (TIME) and a worse prognosis, for …

Background/Aim: Wilms' tumors are pediatric renal tumors that generally have a good
prognosis and outcomes. Viral illnesses have been linked to development of neoplasms and …