Altered dendritic spines are characteristic of traumatized or diseased brain. Two general
categories of spine pathology can be distinguished: pathologies of distribution and …

In this review first we evaluate evidence on the role of the neurobiological alterations
induced by chronic ethanol consumption in the development of ethanol tolerance …

New neurons continue to be born in the subgranular zone (SGZ) of the dentate gyrus in the
hippocampus of adult mammals, including humans. Previous work has shown that …

Recent advances in neuroscience have made it possible to investigate the pathophysiology
of alcoholism at a cellular and molecular level. Evidence indicates that ethanol affects …

The withdrawal syndrome in alcohol-dependent patients appears to be a major stressful
event whose intensity increases with repetition of detoxifications according to a kindling …

Hippocampal neurogenesis is known as the formation of new neurons from the proliferating
neural progenitor cells (NPC) at the dentate gyrus. Cell proliferation, survival, differentiation …

Adult neurogenesis is now widely accepted as an important contributor to hippocampal
integrity and function but also dysfunction when adult neurogenesis is affected in …

Problematic alcohol drinking and alcohol dependence are an increasing health problem
worldwide. Alcohol abuse is responsible for approximately 5% of the total deaths in the …

Background Previous investigations of executive function in alcohol dependent and in social
drinkers have not always produced consistent results and have not utilised key indicators of …

Background. Experimental undernutrition in animals, during the critical brain development
period, produces retardation of brain growth as well as a number of different morphologic …