It is estimated that 2% to 3% of the population are currently prescribed systemic or topical
glucocorticoid treatment. The potent anti-inflammatory action of glucocorticoids to deliver …

Cushing's syndrome is a rare disorder resulting from prolonged exposure to excess
glucocorticoids. Early diagnosis and treatment of Cushing's syndrome is associated with a …

Cushing's syndrome results from lengthy and inappropriate exposure to excessive
glucocorticoids. Untreated, it has significant morbidity and mortality. The syndrome remains …

Context: The metabolic syndrome (MetS) is a cluster of metabolic abnormalities that
increase the risk for type 2 diabetes mellitus and vascular disease. The common …

Objective Cushing's disease (CD) is a rare endocrine disorder characterized by excess
secretion of ACTH due to a pituitary adenoma. Current treatment options are limited and …

Cushing syndrome results from supraphysiological exposure to glucocorticoids and is
associated with significant morbidity and mortality. The pathogenesis includes …

The hypothalamic-pituitary-adrenal (HPA) axis is a classic neuroendocrine system. One of
the best ways to understand the HPA axis is to appreciate its dynamics in the variety of …

Cushing's syndrome is associated with increased mortality, mainly due to cardiovascular
complications, which are sustained by the common development of systemic arterial …

Cushing's syndrome is a rare endocrine disease characterized by cortisol hypersecretion,
induced mainly by a pituitary tumor (Cushing's disease) or, rarely, by an adrenal or an …

Cushing's syndrome refers to the clinical manifestations induced by chronic exposure to
excess glucocorticoids. There are three pathological conditions that can result in the chronic …