Biological and physiological role of reactive oxygen species–the good, the bad and the ugly

L Zuo, T Zhou, BK Pannell, AC Ziegler… - Acta …, 2015 - Wiley Online Library
Reactive oxygen species (ROS) are chemically reactive molecules that are naturally
produced within biological systems. Research has focused extensively on revealing the …

Lung glutathione and oxidative stress: implications in cigarette smoke-induced airway disease

I Rahman, W MacNee - American Journal of Physiology …, 1999 - journals.physiology.org
Glutathione (GSH), a ubiquitous tripeptide thiol, is a vital intra-and extracellular protective
antioxidant in the lungs. The rate-limiting enzyme in GSH synthesis is γ-glutamylcysteine …

沐舒坦对呼吸系统的保护作用及机制

朱科明, 邓小明 - 上海医学, 2000 - cqvip.com
of the air ways CriticM review and per~ nM? ch ActK Otoehino—laryngol ltal, 1997, 17 (1
Suppl 56): 3-16 8 Nemcekova E. Nosedova G. Fra~ va S Amb~ xol and prot~ cdve reflexes …

Use of proteomics to demonstrate a hierarchical oxidative stress response to diesel exhaust particle chemicals in a macrophage cell line

GG Xiao, M Wang, N Li, JA Loo, AE Nel - Journal of Biological Chemistry, 2003 - ASBMB
Epidemiological studies demonstrate an association between short term exposure to
ambient particulate matter (PM) and cardiorespiratory morbidity and mortality. Although the …

[图书][B] Lung surfactants: basic science and clinical applications

RH Notter - 2000 - api.taylorfrancis.com
Integrating basic and clinical research on the biophysical and physiological functions of
pulmonary surfactants, this practical reference presents thorough, cutting-edge coverage on …

Regulation of redox glutathione levels and gene transcription in lung inflammation: therapeutic approaches

I Rahman, W MacNee - Free Radical Biology and Medicine, 2000 - Elsevier
Glutathione (l-γ-glutamyl-l-cysteinylglycine, GSH), is a vital intra-and extracellular protective
antioxidant. Glutathione is synthesized from its constituent amino acids by the sequential …

Ambroxol in the 21st century: pharmacological and clinical update

M Malerba, B Ragnoli - Expert opinion on drug metabolism & …, 2008 - Taylor & Francis
Background: Belonging to the group of expectorants, ambroxol is an active substance with a
long history that influences parameters considered to be the basis for the physiological …

Reactive oxygen species as mediators in asthma

PAJ Henricks, FP Nijkamp - Pulmonary pharmacology & therapeutics, 2001 - Elsevier
This review describes production and effects of reactive oxygen species (ROS) on airway
function. ROS are important in many physiological processes but can also have detrimental …

Exercise-associated oxidative stress

CM Deaton, DJ Marlin - Clinical Techniques in Equine Practice, 2003 - Elsevier
During exercise a number of potential sources exist for the production of reactive oxygen
species such as superoxide anions, hydrogen peroxide and hydroxyl radicals. Oxidative …

Fish tolerance to organophosphate-induced oxidative stress is dependent on the glutathione metabolism and enhanced by N-acetylcysteine

S Peña-Llopis, MD Ferrando, JB Peña - Aquatic Toxicology, 2003 - Elsevier
Dichlorvos (2, 2-dichlorovinyl dimethyl phosphate, DDVP) is an organophosphorus (OP)
insecticide and acaricide extensively used to treat external parasitic infections of farmed fish …