Concise review of nickel human health toxicology and ecotoxicology

S Buxton, E Garman, KE Heim, T Lyons-Darden… - Inorganics, 2019 - mdpi.com
Nickel (Ni) metal and Ni compounds are widely used in applications like stainless steel,
alloys, and batteries. Nickel is a naturally occurring element in water, soil, air, and living …

[HTML][HTML] Redox interactions and genotoxicity of metal-based nanoparticles: A comprehensive review

K Mortezaee, M Najafi, H Samadian, H Barabadi… - Chemico-biological …, 2019 - Elsevier
Nanotechnology is a growing science that may provide several new applications for
medicine, food preservation, diagnostic technologies, and sanitation. Despite its beneficial …

Update of the risk assessment of nickel in food and drinking water

EFSA Panel on Contaminants in the Food Chain … - EFSA …, 2020 - Wiley Online Library
Abstract The European Commission asked EFSA to update its previous Opinion on nickel in
food and drinking water, taking into account new occurrence data, the updated benchmark …

Nickel carcinogenesis mechanism: DNA damage

H Guo, H Liu, H Wu, H Cui, J Fang, Z Zuo… - International journal of …, 2019 - mdpi.com
Nickel (Ni) is known to be a major carcinogenic heavy metal. Occupational and
environmental exposure to Ni has been implicated in human lung and nasal cancers …

Nanoparticle effects on stress response pathways and nanoparticle–protein interactions

SJ Cameron, J Sheng, F Hosseinian… - International journal of …, 2022 - mdpi.com
Nanoparticles (NPs) are increasingly used in a wide variety of applications and products;
however, NPs may affect stress response pathways and interact with proteins in biological …

[PDF][PDF] Cobalt nanoparticles trigger ferroptosis-like cell death (oxytosis) in neuronal cells: potential implications for neurodegenerative disease

G Gupta, A Gliga, J Hedberg, A Serra, D Greco… - 2020 - trepo.tuni.fi
The neurotoxicity of hard metal-based nanoparticles (NPs) remains poorly understood.
Here, we deployed the human neuroblastoma cell line SH-SY5Y differentiated or not into …

[HTML][HTML] Mechanism of effects of nickel or nickel compounds on intestinal mucosal barrier

L Huang, F He, B Wu - Chemosphere, 2022 - Elsevier
As an important metal in industry, national defense, and production, nickel widely exists in
nature and is also a necessary trace element for human beings and animals. Nickel …

Nickel oxide nanoparticles induce apoptosis and ferroptosis in airway epithelial cells via ATF3

F Liu, X Cheng, S Wu, B Hu, C Yang… - Environmental …, 2022 - Wiley Online Library
Exposure to nickel oxide nanoparticles (NiONPs), which have been widely produced and
applied in industry, leads to adverse pulmonary and systemic effects. The aim of this study is …

A systematic quality evaluation and review of nanomaterial genotoxicity studies: a regulatory perspective

KM Siivola, MJ Burgum, B Suárez-Merino… - Particle and fibre …, 2022 - Springer
The number of publications in the field of nanogenotoxicology and the amount of
genotoxicity data on nanomaterials (NMs) in several databases generated by European …

From ferroptosis to cuproptosis, and calcicoptosis, to find more novel metals-mediated distinct form of regulated cell death

J Gu, C Guo, J Ruan, K Li, Y Zhou, X Gong, H Shi - Apoptosis, 2024 - Springer
Regulated cell death (RCD), also known as programmed cell death (PCD), plays a critical
role in various biological processes, such as tissue injury/repair, development, and …