There is ample discussion of the relevance of the metabolic syndrome, the definition criteria,
and predictive power. Nevertheless, along with the increasing prevalence of childhood …

Leptin ingested as a component of breast milk is increasingly recognized to play a role in the
postnatal programming of a healthy phenotype in adulthood. Besides its primary function in …

Background. Protein energy malnutrition (PEM), a common cause of secondary immune
deficiency in children, is associated with an increased risk of infections. Very few studies …

The adipokine leptin realizes signal transduction via four different leptin receptor (OB-R)
isoforms. The amount of functionally active OB-R, however, is affected by constitutive …

Eating disorders such as anorexia (AN) and bulimia nervosa (BN) are characterized by
abnormal eating behavior. The essential aspect of AN is that the individual refuses to …

Background The specific roles that gut microbiota, known pathogens, and host energy-
regulating hormones play in the pathogenesis of non-edematous severe acute malnutrition …

In addition to the ascertained efficacy as antidiabetic drug, metformin is increasingly being
used as weight-loss agent in obesity, and as insulin sensitizer in nonalcoholic fatty liver …

Strength training is usually associated with a reduction in fat mass and with muscle
hypertrophy. The aim of the present study was to examine whether the serum free leptin …

Background Severe acute malnutrition (SAM) can be diagnosed using weight-for-height Z-
score (WHZ) and/or mid-upper arm circumference (MUAC). Although some favor using …

The soluble isoform of leptin receptor (sOb-R), secreted by the liver, regulates leptin
bioavailability and bioactivity. Its reduced levels in diet-induced obesity (DIO) contribute to …