[HTML][HTML] Tumor-associated macrophages in human breast, colorectal, lung, ovarian and prostate cancers

I Larionova, G Tuguzbaeva, A Ponomaryova… - Frontiers in …, 2020 - frontiersin.org
Tumor-associated macrophages (TAMs) are major innate immune cells that constitute up to
50% of the cell mass of human tumors. TAMs are highly heterogeneous cells that originate …

[HTML][HTML] Transforming growth factor-β signaling pathway in colorectal cancer and its tumor microenvironment

Y Itatani, K Kawada, Y Sakai - International journal of molecular sciences, 2019 - mdpi.com
Transforming growth factor-beta (TGF-β) signaling is one of the important cellular pathways
that play key roles for tissue maintenance. In particular, it is important in the context of …

[HTML][HTML] The two faces of tumor-associated macrophages and their clinical significance in colorectal cancer

ML Pinto, E Rios, C Durães, R Ribeiro… - Frontiers in …, 2019 - frontiersin.org
Macrophages are one of the immune populations frequently found in colorectal tumors and
high macrophage infiltration has been associated with both better and worst prognosis …

The immune system and cancer evasion strategies: therapeutic concepts

S Muenst, H Läubli, SD Soysal… - Journal of internal …, 2016 - Wiley Online Library
The complicated interplay between cancer and the host immune system has been studied
for decades. New insights into the human immune system as well as the mechanisms by …

Tumor-associated macrophages promote cancer stem cell-like properties via transforming growth factor-beta1-induced epithelial–mesenchymal transition in …

QM Fan, YY Jing, GF Yu, XR Kou, F Ye, L Gao, R Li… - Cancer letters, 2014 - Elsevier
Abstract Tumor-associated macrophages (TAMs), a crucial component of immune cells
infiltrated in tumor microenvironment, have been found to be associated with progression …

[HTML][HTML] Tumor-associated macrophages and regulatory T cells infiltration and the clinical outcome in colorectal cancer

D Waniczek, Z Lorenc, M Śnietura, M Wesecki… - Archivum immunologiae …, 2017 - Springer
The aim of the study is the assessment of the intensity of the infiltration of tumor-associated
macrophages (TAMs) CD68+/iNOS− and Tregs CD8+/FoxP3+ in colorectal cancer (CRC) …

Dual targeted immunotherapy via in vivo delivery of biohybrid RNAi‐peptide nanoparticles to tumor‐associated macrophages and cancer cells

J Conde, C Bao, Y Tan, D Cui… - Advanced functional …, 2015 - Wiley Online Library
Lung cancer is associated with very poor prognosis and considered one of the leading
causes of death worldwide. Here, highly potent and selective biohybrid RNA interference …

The relationship between chemokines CCL2, CCL3, and CCL4 with the tumor microenvironment and tumor-associated macrophage markers in colorectal cancer

M De la Fuente López, G Landskron… - Tumor …, 2018 - journals.sagepub.com
A complex network of chemokines can influence cancer progression with the recruitment
and activation of hematopoietic cells, including macrophages to the supporting tumor stroma …

[PDF][PDF] The role of tumor-associated macrophages in colorectal carcinoma progression

X Zhong, B Chen, Z Yang - Cellular Physiology and Biochemistry, 2018 - karger.com
Tumor-associated macrophages (TAMs) are one of the most abundant immune cells in the
tumor microenvironment, and they play a pivotal role in prompting the various tumor growth …

[HTML][HTML] Macrophage's role in solid tumors: two edges of a sword

A Jahandideh, M Yarizadeh… - Cancer Cell …, 2023 - Springer
The tumor microenvironment is overwhelmingly dictated by macrophages, intimately
affiliated with tumors, exercising pivotal roles in multiple processes, including angiogenesis …