Increased use of reconstruction procedures in orthopedics, due to trauma, tumor, deformity,
degeneration and an aging population, has caused a blossom, not only in surgical …

Tissue engineering is an important therapeutic strategy to be used in regenerative medicine
in the present and in the future. Functional biomaterials research is focused on the …

Nanotechnology refers to the control, manipulation, study and manufacture of structures and
devices at the nanometer size range. The small size, customized surface, improved solubility …

The development of responsive biomaterials capable of demonstrating modulated function
in response to dynamic physiological and mechanical changes in vivo remains an important …

Mesenchymal stem cells (MSC) are multipotent cells, functioning as precursors to a variety
of cell types including adipocytes, osteoblasts, and chondrocytes. Between osteogenic and …

The controlled delivery of growth factors and cells within biomaterial carriers can enhance
and accelerate functional bone formation. The carrier system can be designed with pre …

Bone morphogenetic proteins (BMPs) are responsible for bone formation during
embryogenesis and bone regeneration and remodeling. The osteoinductive action of BMPs …

The major Food and Drug Association–approved osteoinductive factors in wide clinical use
are bone morphogenetic proteins (BMPs). Although BMPs can promote robust bone …

Mesenchymal stem cell (MSC)-based transplantation is a promising therapeutic approach
for bone regeneration and repair. In the realm of therapeutic bone regeneration, the defect …

Over the last few years, significant research has been conducted in the construction of
artificial bone scaffolds. In the present study, different types of polymer scaffolds, such as …