[HTML][HTML] Molecular mechanisms: connections between nonalcoholic fatty liver disease, steatohepatitis and hepatocellular carcinoma

T Kanda, T Goto, Y Hirotsu, R Masuzaki… - International journal of …, 2020 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD), including nonalcoholic steatohepatitis (NASH),
causes hepatic fibrosis, cirrhosis and hepatocellular carcinoma (HCC). The patatin-like …

[HTML][HTML] Effects of antidiabetic drugs on gut microbiota composition

SA Montandon, FR Jornayvaz - Genes, 2017 - mdpi.com
Gut microbiota forms a catalog of about 1000 bacterial species; which mainly belong to the
Firmicutes and Bacteroidetes phyla. Microbial genes are essential for key metabolic …

Oat phenolic compounds regulate metabolic syndrome in high fat diet-fed mice via gut microbiota

L Dong, C Qin, Y Li, Z Wu, L Liu - Food Bioscience, 2022 - Elsevier
This study aimed to better understand the beneficial effect of oat phenolic compounds (OPC)
in improving metabolic syndrome via regulating metabolites and gut microbiota composition …

Targeting the human gut microbiome with small-molecule inhibitors

AYM Woo, MA Aguilar Ramos, R Narayan… - Nature Reviews …, 2023 - nature.com
The human gut microbiome is a complex microbial community that is strongly linked to both
host health and disease. However, the detailed molecular mechanisms underlying the …

[HTML][HTML] Bi-directional drug-microbiome interactions of anti-diabetics

A Whang, R Nagpal, H Yadav - EBioMedicine, 2019 - thelancet.com
Abstract Type 2 diabetes (T2D) has become a global epidemic. Although several drugs are
available to manage T2D, problems associated with person-to-person variability in drug …

Response of gut microbiota in type 2 diabetes to hypoglycemic agents

F Zhang, M Wang, J Yang, Q Xu, C Liang, B Chen… - Endocrine, 2019 - Springer
Purpose Accumulated evidence has indicated that the gut microbiome affected the
pharmacology of anti-diabetic agents, and their metabolic products induced by the agents …

[HTML][HTML] Age-and diet-specific effects of chronic exposure to chlorpyrifos on hormones, inflammation and gut microbiota in rats

JW Li, B Fang, GF Pang, M Zhang, FZ Ren - Pesticide biochemistry and …, 2019 - Elsevier
Chlorpyrifos is a pesticide frequently detected in food and has been reported to disturb
endocrine and gut health, which was regulated by gut microbiota and enteroendocrine cells …

[HTML][HTML] Crosstalk between gut microbiota and antidiabetic drug action

Y Kyriachenko, T Falalyeyeva, O Korotkyi… - World journal of …, 2019 - ncbi.nlm.nih.gov
Abstract Type 2 diabetes (T2D) is a disorder characterized by chronic inflated blood glucose
levels (hyperglycemia), at first due to insulin resistance and unregulated insulin secretion …

[HTML][HTML] Endotoxemia by Porphyromonas gingivalis Injection Aggravates Non-alcoholic Fatty Liver Disease, Disrupts Glucose/Lipid Metabolism, and Alters Gut …

N Sasaki, S Katagiri, R Komazaki, K Watanabe… - Frontiers in …, 2018 - frontiersin.org
Many risk factors related to the development of non-alcoholic fatty liver disease (NAFLD)
have been proposed, including the most well-known of diabetes and obesity as well as …

[HTML][HTML] Effects of oral glucose-lowering agents on gut microbiota and microbial metabolites

D Wang, J Liu, L Zhou, Q Zhang, M Li… - Frontiers in …, 2022 - frontiersin.org
The current research and existing facts indicate that type 2 diabetes mellitus (T2DM) is
characterized by gut microbiota dysbiosis and disturbed microbial metabolites. Oral glucose …