Current standards of care in glioblastoma therapy

C Fernandes, A Costa, L Osório, RC Lago… - Exon …, 2017 - exonpublications.com
Glioblastoma (GBM) is the most common primary malignant brain tumor in adults.
Regardless of ideal multidisciplinary treatment, including maximal surgical resection …

Maximizing safe resection of low-and high-grade glioma

SL Hervey-Jumper, MS Berger - Journal of neuro-oncology, 2016 - Springer
Surgical resection plays a central role in the management of gliomas. In this study, we
review the evidence in support of extent of resection to improve survival, symptom …

Awake craniotomy to maximize glioma resection: methods and technical nuances over a 27-year period

SL Hervey-Jumper, J Li, D Lau, AM Molinaro… - Journal of …, 2015 - thejns.org
OBJECT Awake craniotomy is currently a useful surgical approach to help identify and
preserve functional areas during cortical and subcortical tumor resections. Methodologies …

Mapping functionally related regions of brain with functional connectivity MR imaging

D Cordes, VM Haughton, K Arfanakis… - American journal …, 2000 - Am Soc Neuroradiology
BACKGROUND AND PURPOSE: In subjects who are performing no prescribed cognitive
task, functional connectivity mapped with MR imaging (fcMRI) shows regions with …

Usefulness of intraoperative electrical subcortical mapping during surgery for low-grade gliomas located within eloquent brain regions: functional results in a …

H Duffau, L Capelle, D Denvil, N Sichez… - Journal of …, 2003 - thejns.org
Object. Although a growing number of authors currently advocate surgery to treat low-grade
gliomas, controversy still persists, especially because of the risk of inducing neurological …

Contrasting acute and slow-growing lesions: a new door to brain plasticity

M Desmurget, F Bonnetblanc, H Duffau - Brain, 2007 - academic.oup.com
The concept of plasticity describes the mechanisms that rearrange cerebral organization
following a brain injury. During the last century, plasticity has been mainly investigated in …

Functional recovery after surgical resection of low grade gliomas in eloquent brain: hypothesis of brain compensation

H Duffau, L Capelle, D Denvil, N Sichez… - Journal of Neurology …, 2003 - jnnp.bmj.com
Objectives: To describe functional recovery after surgical resection of low grade gliomas
(LGG) in eloquent brain areas, and discuss the mechanisms of compensation. Methods …

Language functional magnetic resonance imaging in preoperative assessment of language areas: correlation with direct cortical stimulation

FE Roux, K Boulanouar, JA Lotterie, M Mejdoubi… - …, 2003 - journals.lww.com
OBJECTIVE: The aim of this study was to analyze the usefulness of preoperative language
functional magnetic resonance imaging (fMRI), by correlating fMRI data with intraoperative …

Diffusion-tensor imaging of white matter tracts in patients with cerebral neoplasm

BP Witwer, R Moftakhar, KM Hasan, P Deshmukh… - Journal of …, 2002 - thejns.org
Object. Preserving vital cerebral function while maximizing tumor resection is a principal
goal in surgical neurooncology. Although functional magnetic resonance imaging has been …

Presurgical Functional MR Imaging of Language and Motor Functions: Validation with Intraoperative Electrocortical Mapping1

A Bizzi, V Blasi, A Falini, P Ferroli, M Cadioli, U Danesi… - Radiology, 2008 - pubs.rsna.org
Purpose: To prospectively determine the sensitivity and specificity of functional magnetic
resonance (MR) imaging for mapping language and motor functions in patients with a focal …