Acute canine leptospirosis is well known to vet surgeons. To protect dogs against this lethal
disease, vaccination is widely used. However, chronic forms of leptospirosis have been …

LipL32 is the major outer membrane protein in pathogenic Leptospira. It is highly conserved
throughout pathogenic species and is expressed in vivo during human infection. While these …

Background Infection with pathogenic Leptospira species causes serious systemic
inflammation in patients. Although a few leptospiral proinflammatory molecules have been …

Leptospirosis is a prevalent infectious disease affecting both humans and animals
worldwide. This infection is associated with occupational or recreational exposure to …

Leptospirosis is a bacterial disease affecting several mammalian species, including human
beings. In dogs, it is spread mainly by rodents that act as a maintenance host for several …

The bacillus Calmette–Guerin (BCG), a live attenuated Mycobacterium bovis strain is
considered a promising candidate as a vector system for delivery of foreign antigens to the …

We report in this work that Leptospira strains, virulent L. interrogans serovar Copenhageni,
attenuated L. interrogans serovar Copenhageni and saprophytic L. biflexa serovar Patoc are …

The role of TlyA, TlyB and TlyC proteins in the biology of Leptospira is still uncertain.
Although these proteins have been considered as putative hemolysins, we demonstrate that …

Pathogenic members of the genus Leptospira are the causative agents of leptospirosis, a
neglected disease of public and veterinary health concern. Leptospirosis is a systemic …

Aptamers are nucleic acids that can bind with high affinity and specificity to a range of target
molecules. However, their functionality relies on their secondary and tertiary structures such …