Therapeutic potential of flavonoids in pain and inflammation: mechanisms of action, pre-clinical and clinical data, and pharmaceutical development
Pathological pain can be initiated after inflammation and/or peripheral nerve injury. It is a
consequence of the pathological functioning of the nervous system rather than only a …
consequence of the pathological functioning of the nervous system rather than only a …
Citrus flavonoids and their antioxidant evaluation
The antioxidant ability is the link and bridge connecting a variety of biological activities.
Citrus flavonoids play an essential role in regulating oxidative stress and are an important …
Citrus flavonoids play an essential role in regulating oxidative stress and are an important …
Health-promoting effects of the citrus flavanone hesperidin
C Li, H Schluesener - Critical reviews in food science and nutrition, 2017 - Taylor & Francis
Hesperidin, a member of the flavanone group of flavonoids, can be isolated in large
amounts from the rinds of some citrus species. Considering the wide range of …
amounts from the rinds of some citrus species. Considering the wide range of …
Nutraceuticals: facts and fiction
Epidemiological studies show a link between the consumption of plant-derived foods and a
range of health benefits. These benefits have been associated, at least partially, to some of …
range of health benefits. These benefits have been associated, at least partially, to some of …
Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin—A mini-review
Hesperidin (Hsd) and its aglycone, hesperetin (Hst), are two flavonoids from citrus species
that have various biological properties. Over the past decade, a large number of papers …
that have various biological properties. Over the past decade, a large number of papers …
Pharmacological significance of hesperidin and hesperetin, two citrus flavonoids, as promising antiviral compounds for prophylaxis against and combating COVID-19
PK Agrawal, C Agrawal… - Natural Product …, 2021 - journals.sagepub.com
Hesperidin and hesperetin are flavonoids that are abundantly present as constituents of
citrus fruits. These compounds have attracted attention as several computational methods …
citrus fruits. These compounds have attracted attention as several computational methods …
Progress of research on the role of active ingredients of Citri Reticulatae Pericarpium in liver injury
S Gao, X Chen, Z Yu, R Du, B Chen, Y Wang, X Cai… - Phytomedicine, 2023 - Elsevier
Background Liver is a vital organ responsible for metabolizing and detoxifying both
endogenous and exogenous substances in the body. However, it is susceptible to damage …
endogenous and exogenous substances in the body. However, it is susceptible to damage …
Acute and sub-chronic oral toxicity studies of hesperidin isolated from orange peel extract in Sprague Dawley rats
Y Li, AD Kandhare, AA Mukherjee… - Regulatory Toxicology …, 2019 - Elsevier
Citrus sinensis contains glycoside hesperetin-7-rhamnoglucoside (hesperidin) which harbor
an array of therapeutic potentials including antioxidant, anticancer, and anti-inflammatory …
an array of therapeutic potentials including antioxidant, anticancer, and anti-inflammatory …
Hesperidin, a flavanoglycone attenuates experimental diabetic neuropathy via modulation of cellular and biochemical marker to improve nerve functions
A Visnagri, AD Kandhare, S Chakravarty… - Pharmaceutical …, 2014 - Taylor & Francis
Aim: Diabetic neuropathy (DN) is one of the most common long-term complications of
diabetes mellitus and clinically can be characterized by an elevated nociceptive response …
diabetes mellitus and clinically can be characterized by an elevated nociceptive response …
[HTML][HTML] Hesperidin, a plant flavonoid accelerated the cutaneous wound healing in streptozotocin-induced diabetic rats: Role of TGF-ß/Smads and Ang-1/Tie-2 …
Background: Delayed wound healing is a diverse, multifactorial, complex and inter-related
complication of diabetes resulting in significant clinical morbidity. Hesperidin possesses …
complication of diabetes resulting in significant clinical morbidity. Hesperidin possesses …