Nanoparticles for SPECT and PET imaging: towards personalized medicine and theranostics

A Polyak, TL Ross - Current medicinal chemistry, 2018 - ingentaconnect.com
Background: PET and SPECT imaging methods can be of excellent assistance for the
development of new nanoparticle drug delivery systems, and at the same time, these …

Breast cancer: early diagnosis and effective treatment by drug delivery tracing

M Shamsi, JP Islamian - Nuclear Medicine Review, 2017 - journals.viamedica.pl
Breast cancer is the most frequent cancer in women and it is the main reason of cancer-
related deaths of women worldwide. Different types of breast cancer diagnostic …

177Lu-labeled cyclic RGD peptide as an imaging and targeted radionuclide therapeutic agent in non-small cell lung cancer: biological evaluation and preclinical …

N Pirooznia, K Abdi, D Beiki, F Emami, SS Arab… - Bioorganic …, 2020 - Elsevier
Non-small cell lung carcinoma (NSCLC) is among the most lethal lung cancers responsible
for 80–85% of death. α v β 3 integrin receptor subtype has been identified as a lung cancer …

Technetium-99 m radiolabeled paclitaxel as an imaging probe for breast cancer in vivo

LOF Monteiro, RS Fernandes, LC Castro… - Biomedicine & …, 2017 - Elsevier
The high incidence and mortality of breast cancer supports efforts to develop innovative
imaging probes to effectively diagnose, evaluate the extent of the tumor, and predict the …

Technetium-99m-labeled doxorubicin as an imaging probe for murine breast tumor (4T1 cell line) identification

RS Fernandes, J de Oliveira Silva… - Nuclear medicine …, 2016 - journals.lww.com
Objective Early diagnosis of malignant tumors is essential to successfully plan a radical and
curative approach. In this study we describe the direct radiolabeling of doxorubicin (DOX) at …

Gold nanoparticles for 99mTc-doxorubicin delivery: formulation, in vitro characterization, comparative studies in vivo stability and biodistribution

DM El-Safoury, AB Ibrahim, DA El-Setouhy… - … of Radioanalytical and …, 2021 - Springer
Abstract The [99m Tc] Tc-Doxorubicin–Gold Nanoparticles (99m Tc-Dox-AuNPs) was
formulated as a nanoradiopharmaceutical by different loading procedures to enhance tumor …

Internal dosimetry of 64Cu-DOX-loaded microcapsules by Monte Carlo method

S Heidari, M Sadeghi, M Akhlaghi, D Beiki… - Applied Radiation and …, 2023 - Elsevier
Some of the issues regarding introducing new radiocompounds in nuclear medicine are the
distribution patterns, delivered dose to different organs, diagnostic abilities and side effects …

Development of a single vial kit formulation of [99mTc]‐labeled doxorubicin for tumor imaging and treatment response assessment‐preclinical evaluation and …

P Kumar, B Singh, A Ghai, PP Hazari… - Journal of Labelled …, 2015 - Wiley Online Library
The present study describes the successful radiolabeling of [99mTcO− 4] with doxorubicin,
and the resultant product was formulated in to a ready‐to‐label lyophilized single vial kit …

Use of 99mTc-doxorubicin scintigraphy in females with breast cancer: a pilot study

FI Araujo, FPP Proença, CG Ferreira… - The British journal of …, 2015 - academic.oup.com
Objective: Doxorubicin (Eurofarma, São Paulo, Brazil) is an antitumour agent widely used in
the treatment of breast cancer and can be used for tumour tracking when labelled with a …

[HTML][HTML] Administration of 99mTc-DTPA in combination with doxorubicin alters the radiopharmaceutical biodistribution in rats

T Razaq, H Nisar, S Roohi, A Shehzad… - Iranian Journal of …, 2017 - irjnm.tums.ac.ir
Introduction: Diethylenetriaminepentaacetic acid (DTPA) is a chelating agent used as a
radiopharmaceutical compound, 99mTc-DTPA, for renography. Doxorubicin (DOX) on the …