Sex and gender differences in risk, pathophysiology and complications of type 2 diabetes mellitus

A Kautzky-Willer, J Harreiter, G Pacini - Endocrine reviews, 2016 - academic.oup.com
The steep rise of type 2 diabetes mellitus (T2DM) and associated complications go along
with mounting evidence of clinically important sex and gender differences. T2DM is more …

[HTML][HTML] Intrauterine growth restriction: Clinical consequences on health and disease at adulthood

JB Armengaud, C Yzydorczyk, B Siddeek… - Reproductive …, 2021 - Elsevier
Intrauterine growth restriction (IUGR) affects 10–15% of all pregnancies worldwide. IUGR
may result from maternal, placental or fetal origin. Maternal malnutrition before and during …

[PDF][PDF] Developmental programming of fetal growth and development

LP Reynolds, PP Borowicz, JS Caton… - Veterinary Clinics of …, 2019 - Elsevier
Although the large data sets combining birth and placental weights, maternal and postnatal
nutrition, and health records are sparse for food animals, many controlled studies have …

Preeclampsia and cardiovascular risk for offspring

W Wojczakowski, Ż Kimber-Trojnar, F Dziwisz… - Journal of Clinical …, 2021 - mdpi.com
There is growing evidence of long-term cardiovascular sequelae in children after in utero
exposure to preeclampsia. Maternal hypertension and/or placental ischaemia during …

Maternal obesity increases the risk of metabolic disease and impacts renal health in offspring

SJ Glastras, H Chen, CA Pollock, S Saad - Bioscience reports, 2018 - portlandpress.com
Obesity, together with insulin resistance, promotes multiple metabolic abnormalities and is
strongly associated with an increased risk of chronic disease including type 2 diabetes …

Gestational chronodisruption impairs circadian physiology in rat male offspring, increasing the risk of chronic disease

N Mendez, D Halabi, C Spichiger, ER Salazar… - …, 2016 - academic.oup.com
Chronic exposure to light at night, as in shift work, alters biological clocks (chronodisruption),
negatively impacting pregnancy outcome in humans. Actually the interaction of maternal and …

Pregnancy as a critical window for blood pressure regulation in mother and child: Programming and reprogramming

ND Paauw, BB van Rijn, AT Lely, JA Joles - Acta Physiologica, 2017 - Wiley Online Library
Pregnancy is a critical time for long‐term blood pressure regulation in both mother and child.
Pregnancies complicated by placental insufficiency, resulting in pre‐eclampsia and …

Mechanisms linking exposure to preeclampsia in utero and the risk for cardiovascular disease

PH Andraweera, KL Gatford, AS Care… - … origins of health and …, 2020 - cambridge.org
Preeclampsia (PE) is now recognised as a cardiovascular risk factor for women. Emerging
evidence suggests that children exposed to PE in utero may also be at increased risk of …

Gestational chronodisruption leads to persistent changes in the rat fetal and adult adrenal clock and function

ER Salazar, HG Richter, C Spichiger… - The Journal of …, 2018 - Wiley Online Library
Key points Light at night is essential to a 24/7 society, but it has negative consequences on
health. Basically, light at night induces an alteration of our biological clocks, known as …

Aberrant DNA methylation mediates the transgenerational risk of metabolic and chronic disease due to maternal obesity and overnutrition

Y Li, CA Pollock, S Saad - Genes, 2021 - mdpi.com
Maternal obesity is a rapidly evolving universal epidemic leading to acute and long-term
medical and obstetric health issues, including increased maternal risks of gestational …