Vimentin is a protein that has been linked to a large variety of pathophysiological conditions,
including cataracts, Crohn's disease, rheumatoid arthritis, HIV and cancer. Vimentin has also …

Vimentin is an intermediate filament protein that plays key roles in integration of cytoskeletal
functions, and therefore in basic cellular processes such as cell division and migration …

Intermediate filaments (IFs) are integral components of the cytoskeleton. They provide cells
with tissue-specific mechanical properties and are involved in numerous cellular processes …

Epidemics caused by viral infections pose a significant global threat. Cytoskeletal vimentin is
a major intermediate filament (IF) protein, and is involved in numerous functions, including …

The innate immune response to viruses is critical for the correct establishment of protective
adaptive immunity. Amongst the many pathways involved, the NLRP3 [nucleotide-binding …

Intermediate filaments (IFs) are integral components of the cytoskeleton. They provide cells
with tissue-specific mechanical properties and are involved in numerous cellular processes …

We and others propose vimentin as a possible cellular target for the treatment of COVID-19.
This innovative idea is so recent that it requires further attention and debate. The significant …

HIV-1 has evolved a plethora of strategies to overcome the cytoskeletal barrier (ie, actin and
intermediate filaments (AFs and IFs) and microtubules (MTs)) to achieve the viral cycle. HIV …

There is an urgent need to understand severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2)-host interactions involved in virus spread and pathogenesis, which might …

The DNA dependent protein kinase (DNA-PK) is a trimeric nuclear complex consisting of a
large protein kinase and the Ku heterodimer. The kinase activity of DNA-PK is required for …