Polymorphism and solvatomorphism 2010
HG Brittain - Journal of pharmaceutical sciences, 2012 - Elsevier
Papers and patents that deal with polymorphism (crystal systems for which a substance can
exist in structures defined by different unit cells and where each of the forms has the same …
exist in structures defined by different unit cells and where each of the forms has the same …
Carvedilol
K Beattie, G Phadke, J Novakovic - Profiles of drug substances, excipients …, 2013 - Elsevier
Abstract Carvedilol ((2RS)-1-(9H-carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy) ethyl] amino]
propan-2-ol), a β1-, β2-, and α1-adrenoreceptor blocker drug with antioxidant and …
propan-2-ol), a β1-, β2-, and α1-adrenoreceptor blocker drug with antioxidant and …
Carvedilol: solubilization and cyclodextrin complexation: a technical note
Carvedilol (Table I) is a non-selective β-blocker indicated in the treatment of mild to
moderate congestive heart failure. It also has vasodilating properties that are mainly …
moderate congestive heart failure. It also has vasodilating properties that are mainly …
Determination of the optimal molar ratio in amino acid-based coamorphous systems
J Liu, T Rades, H Grohganz - Molecular Pharmaceutics, 2020 - ACS Publications
Coamorphous drug formulations are a promising approach to improve solubility and
bioavailability of poorly water-soluble drugs. On the basis of theoretical assumptions …
bioavailability of poorly water-soluble drugs. On the basis of theoretical assumptions …
Solving the computational puzzle: Toward a pragmatic pathway for modeling low-energy vibrational modes of pharmaceutical crystals
Five pharmaceutically relevant compounds with increasing molecular complexity, benzoic
acid, diphenylacetic acid, l-tyrosine, celecoxib (form III), and carvedilol (form II), were …
acid, diphenylacetic acid, l-tyrosine, celecoxib (form III), and carvedilol (form II), were …
Pharmaceutical Salts of Carvedilol with Increased Solubility as an Approach for Enhancing the Drug Action
JA Pereira, LF Diniz, C W. Lehmann… - Crystal Growth & …, 2024 - ACS Publications
Carvedilol (CVD) is a β-blocker antihypertensive drug commonly used to treat
cardiovascular disorders. Since the poor oral bioavailability of CVD can be improved directly …
cardiovascular disorders. Since the poor oral bioavailability of CVD can be improved directly …
An insight into carvedilol solid forms: effect of supramolecular interactions on the dissolution profiles
Carvedilol, a β-blocker drug used to treat hypertension, is known to exhibit polymorphism.
Thus far, the crystal structure of two polymorphs (I and II) and one hydrate have been …
Thus far, the crystal structure of two polymorphs (I and II) and one hydrate have been …
Formation of pharmaceutical salts and cocrystals via vapour-assisted tumbling (VAT)–a solvent efficient process
Crystallisations on both the academic and industrial scale often use large volumes of
solvent. In order to decrease the environmental impact of such processes, new techniques …
solvent. In order to decrease the environmental impact of such processes, new techniques …
[HTML][HTML] Application of advanced thermal analysis for characterization of crystalline and amorphous phases of carvedilol
M Skotnicki, A Czerniecka-Kubicka, G Neilsen… - … of Pharmaceutical and …, 2022 - Elsevier
The thermal behaviour of crystalline and amorphous carvedilol (CAR) phases was studied
by advanced thermal analysis using Quantum Design Physical Property Measurement …
by advanced thermal analysis using Quantum Design Physical Property Measurement …
Thermal behavior and molecular mobility studies in the supercooled liquid and glassy states of carvedilol and loratadine
MT Viciosa, JJM Ramos, HP Diogo - International Journal of Pharmaceutics, 2020 - Elsevier
The thermal behavior of carvedilol and loratadine was studied by differential scanning
calorimetry (DSC). The glass-forming ability, as well as the the tendency for crystallization …
calorimetry (DSC). The glass-forming ability, as well as the the tendency for crystallization …