Despite the best available medical treatments, many patients continue to be disabled by
neurologic and psychiatric disorders, resulting in a large unmet need. Advances in imaging …

Brain stimulation (BStim) encompasses multiple modalities (eg, deep brain stimulation,
responsive neurostimulation) that utilize electrodes implanted in deep brain structures to …

Deficits in cognitive control—that is, in the ability to withhold a default pre-potent response in
favour of a more adaptive choice—are common in depression, anxiety, addiction and other …

Psychiatric neurosurgery teams in the United States and Europe have studied deep brain
stimulation (DBS) of the ventral anterior limb of the internal capsule and adjacent ventral …

BACKGROUND: Prior promising results have been reported with deep brain stimulation
(DBS) of the anterior limb of the internal capsule in cases with severe obsessive compulsive …

OBJECTIVE: To investigate the effects of unilateral deep brain stimulation (DBS) in the right
nucleus accumbens in patients with obsessive-compulsive disorder (OCD). Predominantly …

DBS depends on precise placement of the stimulating electrode into an appropriate target
region. Image-based (direct) targeting has been limited by the ability of current technology to …

Obsessive-compulsive disorder (OCD) is a chronic psychiatric disorder that affects 2% of the
general population. Despite optimal cognitive-behavioral and pharmacologic therapy …

Deep brain electrical stimulation has become a recognized therapy in the treatment of a
variety of motor disorders and has potentially promising applications in a wide range of …

Deep brain stimulation (DBS) has been proposed for severe, chronic, treatment-refractory
obsessive-compulsive disorder (OCD) patients. Although serious adverse events can occur …