Association between arterial stiffness, cerebral small vessel disease and cognitive impairment: a systematic review and meta-analysis

TT van Sloten, AD Protogerou, RMA Henry… - Neuroscience & …, 2015 - Elsevier
Arterial stiffness may be a cause of cerebral small vessel disease and cognitive impairment.
We therefore performed a systematic review and meta-analysis of studies on the association …

Cerebral microbleeds: a review of clinical, genetic, and neuroimaging associations

PA Yates, VL Villemagne, KA Ellis… - Frontiers in …, 2014 - frontiersin.org
Cerebral microbleeds (microbleeds) are small, punctuate hypointense lesions seen in T2*
Gradient-Recall Echo (GRE) and Susceptibility-Weighted (SWI) Magnetic Resonance …

Arterial stiffness and cerebral small vessel disease: the Rotterdam Scan Study

MMF Poels, K Zaccai, GC Verwoert, MW Vernooij… - Stroke, 2012 - Am Heart Assoc
Background and Purpose—Aging and vascular risk factors contribute to arterial stiffening.
Increased arterial stiffness exposes the small vessels in the brain to abnormal flow …

Magnetic resonance imaging of cardiovascular function and the brain: is dementia a cardiovascular-driven disease?

A de Roos, J van der Grond, G Mitchell, J Westenberg - Circulation, 2017 - Am Heart Assoc
The proximal aorta acts as a coupling device between heart and brain perfusion, modulating
the amount of pressure and flow pulsatility transmitted into the cerebral microcirculation …

Cerebral small vessel disease and arterial stiffness: tsunami effect in the brain

N Saji, K Toba, T Sakurai - Pulse, 2016 - karger.com
Background: Cerebral small vessel diseases, including silent lacunar infarcts, white matter
hyperintensities, and microbleeds, pose a risk for cerebrovascular disease, cognitive …

The relationship of brachial-ankle pulse wave velocity to future cardiovascular disease events in the general Japanese population: the Takashima Study

N Takashima, TC Turin, K Matsui, N Rumana… - Journal of human …, 2014 - nature.com
Brachial-ankle pulse wave velocity (baPWV) is a non-invasive measure of arterial stiffness
obtained using an automated system. Although baPWVs have been widely used as a non …

[HTML][HTML] Dysfunction of the blood-brain barrier in cerebral microbleeds: from bedside to bench

H Wang, C Zhang, Y Qiu, A Chen, Y Li, B Hu - Aging and disease, 2021 - ncbi.nlm.nih.gov
Cerebral microbleeds (CMBs) are a disorder of cerebral microvessels that are characterized
as small (< 10 mm), hypointense, round or ovoid lesions seen on T2*-weighted gradient …

[HTML][HTML] Recent progress in vascular aging: mechanisms and its role in age-related diseases

X Xu, B Wang, C Ren, J Hu, DA Greenberg… - Aging and …, 2017 - ncbi.nlm.nih.gov
As with many age-related diseases including vascular dysfunction, age is considered an
independent and crucial risk factor. Complicated alterations of structure and function in the …

[HTML][HTML] Cerebral microbleeds: their associated factors, radiologic findings, and clinical implications

BJ Kim, SH Lee - Journal of stroke, 2013 - ncbi.nlm.nih.gov
Cerebral microbleeds (CMBs) are tiny, round dark-signal lesions that are most often
detected on gradient-echo MR images. CMBs consist of extravasations of blood components …

Effect of genetic depletion of MMP-9 on neurological manifestations of hypertension-induced intracerebral hemorrhages in aged mice

S Tarantini, A Yabluchanskiy, ML Lindsey, A Csiszar… - Geroscience, 2021 - Springer
Clinical and experimental studies show that hypertension induces intracerebral
hemorrhages (ICH), including cerebral microhemorrhages in the aged brain, which …