Regulation of cerebral blood flow in humans: physiology and clinical implications of autoregulation

JAHR Claassen, DHJ Thijssen… - Physiological …, 2021 - journals.physiology.org
Brain function critically depends on a close matching between metabolic demands,
appropriate delivery of oxygen and nutrients, and removal of cellular waste. This matching …

Impact of hypertension on cognitive function: a scientific statement from the American Heart Association

C Iadecola, K Yaffe, J Biller, LC Bratzke, FM Faraci… - …, 2016 - Am Heart Assoc
Background—Age-related dementia, most commonly caused by Alzheimer disease or
cerebrovascular factors (vascular dementia), is a major public health threat. Chronic arterial …

Guidelines for the management of pediatric severe traumatic brain injury: update of the brain trauma foundation guidelines

PM Kochanek, RC Tasker, N Carney… - Pediatric Critical Care …, 2019 - journals.lww.com
Any opinions, findings, and conclusions or recommendations expressed in this material are
those of the authors and do not necessarily reflect the views of the US Army Contracting …

Transfer function analysis of dynamic cerebral autoregulation: a CARNet white paper 2022 update

RB Panerai, P Brassard, JS Burma… - Journal of Cerebral …, 2023 - journals.sagepub.com
Cerebral autoregulation (CA) refers to the control of cerebral tissue blood flow (CBF) in
response to changes in perfusion pressure. Due to the challenges of measuring intracranial …

Posterior reversible encephalopathy syndrome: clinical and radiological manifestations, pathophysiology, and outstanding questions

JE Fugate, AA Rabinstein - The Lancet Neurology, 2015 - thelancet.com
Almost two decades have elapsed since posterior reversible encephalopathy syndrome
(PRES) was described in an influential case series. This usually reversible clinical syndrome …

Vascular contributions to cognitive impairment and dementia: a statement for healthcare professionals from the American Heart Association/American Stroke …

PB Gorelick, A Scuteri, SE Black, C DeCarli… - stroke, 2011 - Am Heart Assoc
Background and Purpose—This scientific statement provides an overview of the evidence
on vascular contributions to cognitive impairment and dementia. Vascular contributions to …

Transfer function analysis of dynamic cerebral autoregulation: a white paper from the International Cerebral Autoregulation Research Network

JAHR Claassen… - Journal of Cerebral …, 2016 - journals.sagepub.com
Cerebral autoregulation is the intrinsic ability of the brain to maintain adequate cerebral
perfusion in the presence of blood pressure changes. A large number of methods to assess …

Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women

K Yaffe, AM Laffan, SL Harrison, S Redline, AP Spira… - Jama, 2011 - jamanetwork.com
Context Sleep-disordered breathing (characterized by recurrent arousals from sleep and
intermittent hypoxemia) is common among older adults. Cross-sectional studies have linked …

Aging of cerebral white matter

H Liu, Y Yang, Y Xia, W Zhu, RK Leak, Z Wei… - Ageing research …, 2017 - Elsevier
White matter (WM) occupies a large volume of the human cerebrum and is mainly composed
of myelinated axons and myelin-producing glial cells. The myelinated axons within WM are …

Cerebral microvascular pathology in ageing and neurodegeneration

WR Brown, CR Thore - Neuropathology and applied …, 2011 - Wiley Online Library
WR Brown and CR Thore (2011) Neuropathology and Applied Neurobiology37, 56–74
Cerebral microvascular pathology in ageing and neurodegeneration This review of age …