An overview of the main genetic, epigenetic and environmental factors involved in autism spectrum disorder focusing on synaptic activity

E Masini, E Loi, AF Vega-Benedetti, M Carta… - International journal of …, 2020 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder that affects social
interaction and communication, with restricted interests, activity and behaviors. ASD is highly …

Environmental risk factors for autism: an evidence-based review of systematic reviews and meta-analyses

A Modabbernia, E Velthorst, A Reichenberg - Molecular autism, 2017 - Springer
Background According to recent evidence, up to 40–50% of variance in autism spectrum
disorder (ASD) liability might be determined by environmental factors. In the present paper …

Autism spectrum disorders and autistic traits: a decade of new twin studies

A Ronald, RA Hoekstra - … Journal of Medical Genetics Part B …, 2011 - Wiley Online Library
Researchers continue to pursue a better understanding of the symptoms, comorbidities, and
causes of autism spectrum disorders. In this article we review more than 30 twin studies of …

The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood

P Lichtenstein, E Carlström, M Råstam… - American Journal of …, 2010 - Am Psychiatric Assoc
Objective: Autism spectrum disorders are considered to be among the most heritable mental
disorders, a notion based on surprisingly sparse data from small clinical studies. Population …

Evidence that autistic traits show the same etiology in the general population and at the quantitative extremes (5%, 2.5%, and 1%)

EB Robinson, KC Koenen… - Archives of general …, 2011 - jamanetwork.com
Context Genetic factors play an important role in the etiology of both autism spectrum
disorders and autistic traits. However, little is known about the etiologic consistency of …

Autism-related transcription factors underlying the sex-specific effects of prenatal bisphenol a exposure on transcriptome-interactome profiles in the offspring prefrontal …

S Kanlayaprasit, S Thongkorn, P Panjabud… - International Journal of …, 2021 - mdpi.com
Bisphenol A (BPA) is an environmental risk factor for autism spectrum disorder (ASD). BPA
exposure dysregulates ASD-related genes in the hippocampus and neurological functions …

Exploring the relationship between autistic-like traits and ADHD behaviors in early childhood: findings from a community twin study of 2-year-olds

A Ronald, LR Edelson, P Asherson… - Journal of abnormal child …, 2010 - Springer
Behaviors characteristic of autism and ADHD emerge in early childhood, yet research
investigating their comorbidity has focused on older children. This study aimed to explore …

Infant avoidance during a tactile task predicts autism spectrum behaviors in toddlerhood

MA Mammen, GA Moore, LV Scaramella… - Infant mental health …, 2015 - Wiley Online Library
The experience of touch is critical for early communication and social interaction; infants
who show aversion to touch may be at risk for atypical development and behavior problems …

Particulate matter exposure during pregnancy and infancy and risks of autism spectrum disorder in children: a systematic review and meta-analysis

H Liu, L Ding, G Qu, X Guo, MM Liang, S Ma… - Science of The Total …, 2023 - Elsevier
Purpose This meta-analysis aimed to clarify the relationship between particulate matter (PM)
and autism spectrum disorder (ASD) in detail. Methods A systematic literature search was …

Are autistic traits in the general population stable across development?

AJO Whitehouse, M Hickey, A Ronald - PLoS One, 2011 - journals.plos.org
There is accumulating evidence that autistic traits (AT) are on a continuum in the general
population, with clinical autism representing the extreme end of a quantitative distribution …