Carbohydrate-based macromolecular biomaterials

L Su, Y Feng, K Wei, X Xu, R Liu, G Chen - Chemical Reviews, 2021 - ACS Publications
Carbohydrates are the most abundant and one of the most important biomacromolecules in
Nature. Except for energy-related compounds, carbohydrates can be roughly divided into …

Surface modified cellulose nanomaterials: a source of non-spherical nanoparticles for drug delivery

YY Khine, MH Stenzel - Materials Horizons, 2020 - pubs.rsc.org
Cellulose nanomaterials, often called nanocellulose, have created a lot of buzz as a
renewable building block for new materials such as nanocomposites, aerogels and …

Glycopolymers for drug delivery: opportunities and challenges

MH Stenzel - Macromolecules, 2022 - ACS Publications
Glycopolymers are synthetic polymers with pendant sugars, which hold promise for a range
of biomedical applications ranging from tissue engineering to sensing. The known specific …

Poly (2‐oxazoline)‐and Poly (2‐oxazine)‐Based Self‐Assemblies, Polyplexes, and Drug Nanoformulations—An Update

A Zahoranová, R Luxenhofer - Advanced Healthcare Materials, 2021 - Wiley Online Library
Abstract For many decades, poly (2‐oxazoline) s and poly (2‐oxazine) s, two closely related
families of polymers, have led the life of a rather obscure research topic with only a few …

Loading‐Dependent Structural Model of Polymeric Micelles Encapsulating Curcumin by Solid‐State NMR Spectroscopy

AC Pöppler, MM Lübtow… - Angewandte Chemie …, 2019 - Wiley Online Library
Detailed insight into the internal structure of drug‐loaded polymeric micelles is scarce, but
important for developing optimized delivery systems. We observed that an increase in the …

Think beyond the core: impact of the hydrophilic corona on drug solubilization using polymer micelles

MS Haider, MM Lübtow, S Endres… - … applied materials & …, 2020 - ACS Publications
Polymeric micelles are typically characterized as core–shell structures. The hydrophobic
core is considered as a depot for hydrophobic molecules, and the corona-forming block acts …

The trojan horse goes wild: The effect of drug loading on the behavior of nanoparticles

MH Stenzel - Angewandte Chemie International Edition, 2021 - Wiley Online Library
Drug delivery with nanoparticles is sometimes compared to an attack with a Trojan Horse.
The drugs are hidden in nanoparticles and enter the unsuspecting cells in a stealth‐like …

Correlation between drug loading content and biological activity: the complexity demonstrated in paclitaxel-loaded glycopolymer micelle system

C Cao, J Zhao, M Lu, CJ Garvey… - Biomacromolecules, 2019 - ACS Publications
Drug delivery carriers are now widely established because they can increase the
therapeutic efficiency of drugs. In general, the aim in this field is to create effective carriers …

Drug-directed morphology changes in polymerization-induced self-assembly (PISA) influence the biological behavior of nanoparticles

C Cao, F Chen, CJ Garvey… - ACS applied materials & …, 2020 - ACS Publications
The effect of the hydrophobic block length on the morphologies of polymerization-induced
self-assembled (PISA) nanoparticles is well understood. However, the influence of drug …

Polymersomes in Drug Delivery─ From Experiment to Computational Modeling

Q Xu, Y Wang, Y Zheng, Y Zhu, Z Li, Y Liu… - …, 2023 - ACS Publications
Polymersomes, composed of amphiphilic block copolymers, are self-assembled vesicles
that have gained attention as potential drug delivery systems due to their good …