Allergy affects more than 15% of the world population, and some studies have shown that up
30% of the US population has some form of allergy. Most of these patients have various …

Oral tolerance is classically defined as the suppression of immune responses to antigens
(Ag) that have been administered previously by the oral route. Multiple mechanisms of …

Much progress has been made in the 26 years since initial studies of the first purified
acetylcholine receptors (AChRs) led to the discovery that an antibody‐mediated …

Experimental autoimmune uveoretinitis (EAU), a widely used animal model of human
posterior/pan-uveitis, is extremely valuable in allowing understanding of the pathogenesis of …

Uveitis is a complex ocular inflammatory disease often accompanied by bacterial or viral
infections (infectious uveitis) or underlying autoimmune diseases (non-infectious uveitis) …

Recent studies demonstrated that administration of a p55‐tumor necrosis factor (TNF)
receptor IgG‐fusion protein (TNFR‐IgG) prevented the clinical onset of experimental …

Purpose. Experimental autoimmune uveoretinitis (EAU), an established model for human
endogenous (autoimmune) posterior uveitis, is a CD4+ T cell-mediated disease inducible in …

We have developed nanoparticles (NPs), which are capable of targeting a specific lesion
and gradually releasing the agent at the site over a prolonged time period after a single …

Nasal administration of peptide antigens has been shown to induce T cell tolerance. We
have investigated the potential for peptide therapy of the autoimmune response to myelin …

The purpose of the study was to map the dominant T cell epitope of the CB11 sequence of
CII in RT1u haplotype rats and to determine if, when used as a synthetic peptide, it would …