Lentiviral vectors (LV) have seen considerably increase in use as gene therapy vectors for
the treatment of acquired and inherited diseases. This review presents the state of the art of …

No matter what their origin, strain and family, viruses have evolved exquisite strategies to
reach and penetrate specific target cells where they hijack the cellular machinery to express …

More than two decades have passed since genetically modified HIV was used for gene
delivery. Through continuous improvements these early marker gene-carrying HIVs have …

Хирургия позвоночника один из наиболее сложных разделов травматологии и
ортопедии, и одновременно один из элитных направлений в медицине. При этом …

Lentiviral vectors are tools for gene transfer derived from lentiviruses. From their first
application to now they have been strongly developed in design, in biosafety and in their …

During the last few years, recombinant viral vectors derived from adenovirus (Ad), adeno-
associated virus (AAV) or lentivirus (LV) have been developed into highly effective vehicles …

We exploited the ability of lentiviral vectors to govern the stable transduction of cells
irrespective of their cycling status to induce the reversible immortalization of human primary …

Recent commercialization of lentiviral vector (LV)-based cell therapies and successful
reports of clinical studies have demonstrated the untapped potential of LVs to treat diseases …

Gene transfer vectors based on retroviruses including oncogenic retroviruses and
lentiviruses provide effective means for the delivery, integration and expression of …

Gingivostomatitis (GS) or recurrent oral ulceration (ROU) is found in veterinary patients with
increasing frequency. Severe inflammation of the oral cavity is often seen in feline patients …