[HTML][HTML] Microbiome in cancer: Role in carcinogenesis and impact in therapeutic strategies

MM Rahman, MR Islam, S Shohag, MT Ahasan… - Biomedicine & …, 2022 - Elsevier
Cancer is the world's second-leading cause of death, and the involvement of microbes in a
range of diseases, including cancer, is well established. The gut microbiota is known to play …

Promises and pitfalls of using high‐throughput sequencing for diet analysis

A Alberdi, O Aizpurua, K Bohmann… - Molecular ecology …, 2019 - Wiley Online Library
The application of high‐throughput sequencing‐based approaches to DNA extracted from
environmental samples such as gut contents and faeces has become a popular tool for …

Improved metagenome binning and assembly using deep variational autoencoders

JN Nissen, J Johansen, RL Allesøe, CK Sønderby… - Nature …, 2021 - nature.com
Despite recent advances in metagenomic binning, reconstruction of microbial species from
metagenomics data remains challenging. Here we develop variational autoencoders for …

Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage

RS Hendriksen, P Munk, P Njage, B Van Bunnik… - Nature …, 2019 - nature.com
Antimicrobial resistance (AMR) is a serious threat to global public health, but obtaining
representative data on AMR for healthy human populations is difficult. Here, we use …

Rapid and precise alignment of raw reads against redundant databases with KMA

PTLC Clausen, FM Aarestrup, O Lund - BMC bioinformatics, 2018 - Springer
Background As the cost of sequencing has declined, clinical diagnostics based on next
generation sequencing (NGS) have become reality. Diagnostics based on sequencing will …

[HTML][HTML] A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry

J Chen, X Yang, H Si, Q Gong, T Que, J Li, Y Li, C Wu… - Cell, 2023 - cell.com
It is unknown whether pangolins, the most trafficked mammals, play a role in the zoonotic
transmission of bat coronaviruses. We report the circulation of a novel MERS-like …

Co-diversification of an intestinal Mycoplasma and its salmonid host

JA Rasmussen, P Kiilerich, AS Madhun… - The ISME …, 2023 - academic.oup.com
Understanding the evolutionary relationships between a host and its intestinal resident
bacteria can transform how we understand adaptive phenotypic traits. The interplay between …

The microbiome and cancer

B Goodman, H Gardner - The Journal of pathology, 2018 - Wiley Online Library
Humans coexist with a vast bacterial, fungal and viral microbiome with which we have
coevolved for millions of years. Several long recognized epidemiological associations …

Bioinformatic approaches for studying the microbiome of fermented food

LH Walsh, M Coakley, AM Walsh… - Critical Reviews in …, 2023 - Taylor & Francis
High-throughput DNA sequencing-based approaches continue to revolutionise our
understanding of microbial ecosystems, including those associated with fermented foods …

[HTML][HTML] Platforms for elucidating antibiotic resistance in single genomes and complex metagenomes

CL Gupta, RK Tiwari, E Cytryn - Environment international, 2020 - Elsevier
Antibiotic or antimicrobial resistance (AR) facilitated by the vertical and/or horizontal transfer
of antibiotic resistance genes (ARGs), is a serious global health challenge. While …