Embryonic epithelia achieve complex morphogenetic movements, including in-plane
reshaping, bending and folding, through the coordinated action and rearrangement of …

In native states, animal cells of many types are supported by a fibrous network that forms the
main structural component of the ECM. Mechanical interactions between cells and the 3D …

The conservation of gene networks that specify and differentiate distinct tissues has long
been a subject of great interest to evolutionary developmental biologists, but the question of …

Differential mechanical force distributions are increasingly recognized to provide important
feedback into the control of an organ's final size and shape. As a second messenger that …

Highlights•Amnioserosa cells are functionally and evolutionarily comparable to amnion
cells.•Amnioserosa cells regulate dorsal closure through controlled osmosis and …

Embryonic boundaries are sharp delimitations that prevent intermingling between different
cell populations. They are essential for the development of well-organized structures and …

Despite being a short‐lived, extraembryonic tissue, the amnioserosa plays critical roles in
the major morphogenetic events of Drosophila embryogenesis. These roles involve both …

During Drosophila embryogenesis, the germband first extends to curl around the posterior
end of the embryo and then retracts back; however, retraction is not simply the reversal of …

The cell–cell boundaries of epithelial cells form cellular frameworks at the apical side of
tissues. Deformations in these boundaries, for example, boundary contraction and …

Background: Heat shocks applied at the onset of gastrulation in early Drosophila embryos
frequently lead to phenocopies of U‐shaped mutants—having characteristic failures in the …