Bone remodeling: Multiple cellular interactions required for coupling of bone formation and resorption
The dynamic nature of the skeleton is achieved by a process called “remodeling” which
involves the co-ordinated actions of osteoclasts, osteoblasts, osteocytes within the bone …
involves the co-ordinated actions of osteoclasts, osteoblasts, osteocytes within the bone …
Defining the roles of parathyroid hormone-related protein in normal physiology
WM Philbrick, JJ Wysolmerski… - Physiological …, 1996 - journals.physiology.org
Parathyroid hormone-related protein (PTHrP) was discovered as a result of a search for the
circulating factor secreted by cancers which causes the common paraneoplastic syndrome …
circulating factor secreted by cancers which causes the common paraneoplastic syndrome …
[HTML][HTML] Bone mass, vitamin D deficiency, and hyperparathyroidism in congestive heart failure
E Shane, D Mancini, K Aaronson, SJ Silverberg… - The American journal of …, 1997 - Elsevier
PURPOSE: In contrast to renal and hepatic failure, congestive heart failure (CHF) has not
been associated with a defined metabolic bone disorder. However, low bone mass has …
been associated with a defined metabolic bone disorder. However, low bone mass has …
Parathyroid hormone-related protein, its regulation of cartilage and bone development, and role in treating bone diseases
TJ Martin - Physiological reviews, 2016 - journals.physiology.org
Although parathyroid hormone-related protein (PTHrP) was discovered as a cancer-derived
hormone, it has been revealed as an important paracrine/autocrine regulator in many …
hormone, it has been revealed as an important paracrine/autocrine regulator in many …
Calcium-regulating hormones and parathyroid hormone-related peptide in normal human pregnancy and postpartum: a longitudinal study
MSM Ardawi, HAN Nasrat… - European journal of …, 1997 - academic.oup.com
Objectives To evaluate calcium-regulating hormones and parathyroid hormone-related
peptide (PTHrP) in normal human pregnancy and postpartum in women not deficient in …
peptide (PTHrP) in normal human pregnancy and postpartum in women not deficient in …
Parathyroid hormone-related protein: elevated levels in both humoral hypercalcemia of malignancy and hypercalcemia complicating metastatic breast cancer
V Grill, P Ho, JJ Body, N Johanson… - The Journal of …, 1991 - academic.oup.com
A RIA for PTH-related protein (PTHrP) is described, using a polyclonal goat antiserum
against synthetic PTHrP-(l–40) and recombinant PTHrP-(l–84) as standard. The detection …
against synthetic PTHrP-(l–40) and recombinant PTHrP-(l–84) as standard. The detection …
Molecular mechanisms in coupling of bone formation to resorption
Bone remodeling is the process of removal and replacement of bone, taking place at many
sites throughout the skeleton and regulated mainly by locally generated factors. Its purposes …
sites throughout the skeleton and regulated mainly by locally generated factors. Its purposes …
Parathyroid hormone‐related protein and its receptors: nuclear functions and roles in the renal and cardiovascular systems, the placental trophoblasts and the …
TL Clemens, S Cormier, A Eichinger… - British journal of …, 2001 - Wiley Online Library
The cloning of the so‐called 'parathyroid hormone‐related protein'(PTHrP) in 1987 was the
result of a long quest for the factor which, by mimicking the actions of PTH in bone and …
result of a long quest for the factor which, by mimicking the actions of PTH in bone and …
Parathyroid hormone–related peptide as a local regulator of vascular calcification: its inhibitory action on in vitro calcification by bovine vascular smooth muscle cells
S Jono, Y Nishizawa, A Shioi, H Morii - … , thrombosis, and vascular …, 1997 - Am Heart Assoc
In the present study, we investigated the role of parathyroid hormone–related peptide
(PTHrP) in vascular calcification by using an in vitro calcification model. We demonstrated …
(PTHrP) in vascular calcification by using an in vitro calcification model. We demonstrated …
Osteoblast-derived PTHrP is a physiological regulator of bone formation
TJ Martin - The Journal of clinical investigation, 2005 - Am Soc Clin Investig
Parathyroid hormone–related protein (PTHrP) acts as a paracrine regulator in several
tissues, and its physiological roles also extend to bone. In this issue of the JCI, Miao et al …
tissues, and its physiological roles also extend to bone. In this issue of the JCI, Miao et al …