The Legionella pneumophila Dot/Icm type IV secretion system and its effectors

DC Lockwood, H Amin, TRD Costa… - …, 2022 - microbiologyresearch.org
To prevail in the interaction with eukaryotic hosts, many bacterial pathogens use protein
secretion systems to release virulence factors at the host–pathogen interface and/or deliver …

Anticancer small-molecule agents targeting eukaryotic elongation factor 1A: State of the art

H Zhang, J Cai, S Yu, B Sun, W Zhang - International Journal of …, 2023 - mdpi.com
Eukaryotic elongation factor 1A (eEF1A) canonically delivers amino acyl tRNA to the
ribosomal A site during the elongation stage of protein biosynthesis. Yet paradoxically, the …

Wearable five-finger keyboardless input system based on silk fibroin electronic skin

J Liu, J Chen, F Dai, J Zhao, S Li, Y Shi, W Li, L Geng… - Nano Energy, 2022 - Elsevier
To get rid of the limitations of traditional keyboards, we report a new generation wearable
keyboardless input system (WKIS). Based on the coupling of triboelectrification and …

Immune responses of different COVID-19 vaccination strategies by analyzing single-cell RNA sequencing data from multiple tissues using machine learning methods

H Li, Q Ma, J Ren, W Guo, K Feng, Z Li, T Huang… - Frontiers in …, 2023 - frontiersin.org
Multiple types of COVID-19 vaccines have been shown to be highly effective in preventing
SARS-CoV-2 infection and in reducing post-infection symptoms. Almost all of these vaccines …

Identification of the relationship between hub genes and immune cell infiltration in vascular endothelial cells of proliferative diabetic retinopathy using bioinformatics …

J Huang, Q Zhou - Disease Markers, 2022 - Wiley Online Library
Background. Diabetic retinopathy (DR) is a serious ophthalmopathy that causes blindness,
especially in the proliferative stage. However, the pathogenesis of its effect on endothelial …

[HTML][HTML] The eEF1 family of mammalian translation elongation factors

BS Negrutskii, VF Shalak, OV Novosylna, LV Porubleva… - BBA advances, 2023 - Elsevier
The eEF1 family of mammalian translation elongation factors is comprised of the two
variants of eEF1A (eEF1A1 and eEF1A2), and the eEF1B complex. The latter consists of …

[HTML][HTML] EEF1A1 is Involved the Regulating Neuroinflammatory Processes in Parkinson's Disease

Z Aisha, J Lei, Y Zhang, J Ma - Journal of Integrative Neuroscience, 2023 - imrpress.com
Background: Studies have reported that the RNA-binding protein Eukaryotic Elongation
Factor 1A1 (EEF1A1) is low expressed in the hippocampal region of Alzheimer's disease …

[HTML][HTML] Characterization of cancer subtypes associated with clinical outcomes by multi-omics integrative clustering

V Crippa, F Malighetti, M Villa, A Graudenzi… - Computers in Biology …, 2023 - Elsevier
Cancer patients show heterogeneous phenotypes and very different outcomes and
responses even to common treatments, such as standard chemotherapy. This state-of-affairs …

Oncogenic activation of EEF1A2 expression: a journey from a putative to an established oncogene

SA Patel, MK Hassan, M Dixit - Cellular & Molecular Biology Letters, 2024 - Springer
Protein synthesis via translation is a central process involving several essential proteins
called translation factors. Although traditionally described as cellular “housekeepers,” …

scRNA-seq of cultured human amniotic fluid from fetuses with spina bifida reveals the origin and heterogeneity of the cellular content

A Dasargyri, D González Rodríguez, H Rehrauer… - Cells, 2023 - mdpi.com
Amniotic fluid has been proposed as an easily available source of cells for numerous
applications in regenerative medicine and tissue engineering. The use of amniotic fluid cells …