Structural simplification of natural products
S Wang, G Dong, C Sheng - Chemical Reviews, 2019 - ACS Publications
Natural products (NPs) are important sources of clinical drugs due to their structural diversity
and biological prevalidation. However, the structural complexity of NPs leads to synthetic …
and biological prevalidation. However, the structural complexity of NPs leads to synthetic …
Current applications of Suzuki–Miyaura coupling reaction in the total synthesis of natural products: an update
A Taheri Kal Koshvandi, MM Heravi… - Applied …, 2018 - Wiley Online Library
Suzuki‐Miyaura Coupling Reaction (SMCR) has been extensively used in the total synthesis
of natural products. We underscored these achievements in a report published in …
of natural products. We underscored these achievements in a report published in …
Antimycobacterial natural products
BR Copp - Natural Product Reports, 2003 - pubs.rsc.org
Covering: 1990–2002This review covers the literature published between January 1990 and
December 2002 (inclusive) for natural products with reported antimycobacterial activity, with …
December 2002 (inclusive) for natural products with reported antimycobacterial activity, with …
Natural antimycobacterial metabolites: current status
AL Okunade, MPF Elvin-Lewis, WH Lewis - Phytochemistry, 2004 - Elsevier
Over the years the introduction of very effective drugs has revolutionized the treatment of
tuberculosis. In recent years, however, emerging multiple drug resistance has become a …
tuberculosis. In recent years, however, emerging multiple drug resistance has become a …
Quinoline heterocyclic containing plant and marine candidates against drug-resistant Mycobacterium tuberculosis: A systematic drug-ability investigation
Today, tuberculosis (TB) caused by the acid-fast bacilli, Mycobacterium tuberculosis (Mtb) is
the most infectious killer disease globally with high morbidity and mortality rates. The rapid …
the most infectious killer disease globally with high morbidity and mortality rates. The rapid …
Antimicrobial properties of Honduran medicinal plants
DL Lentz, AM Clark, CD Hufford… - Journal of …, 1998 - Elsevier
Ninety-two plants used in the traditional pharmacopoeia of the Pech and neighboring
Mestizo peoples of central Honduras are reported. The results of in vitro antimicrobial …
Mestizo peoples of central Honduras are reported. The results of in vitro antimicrobial …
Acetylcholinesterase inhibitors for the treatment of Alzheimer's disease–a patent review (2016–present)
M Bortolami, D Rocco, A Messore… - Expert Opinion on …, 2021 - Taylor & Francis
Introduction–AD, the most common form of dementia, has a multifactorial etiology, and the
current therapy (AChEIs and memantine) is unable to interrupt its progress and fatal …
current therapy (AChEIs and memantine) is unable to interrupt its progress and fatal …
High-throughput screen for detecting antimycobacterial agents
GA Chung, Z Aktar, S Jackson… - Antimicrobial agents and …, 1995 - Am Soc Microbiol
A simple, robust assay system which can be used to screen for inhibitors of mycobacterial
growth has been developed. A strain of the rapidly growing saprophyte Mycobacterium …
growth has been developed. A strain of the rapidly growing saprophyte Mycobacterium …
Alkaloids as potential anti-tubercular agents
An increasing incidence of deaths due to tuberculosis and the known drawbacks of the
current existing drugs including the emergence of multi drug-resistant strains have led to a …
current existing drugs including the emergence of multi drug-resistant strains have led to a …
Drug development against tuberculosis: Impact of alkaloids
Despite of the advances made in the treatment and management, tuberculosis (TB) still
remains one of main public health problem. The contrary effects of first and second-line anti …
remains one of main public health problem. The contrary effects of first and second-line anti …