Biological responses to physicochemical properties of biomaterial surface

M Rahmati, EA Silva, JE Reseland… - Chemical Society …, 2020 - pubs.rsc.org
Biomedical scientists use chemistry-driven processes found in nature as an inspiration to
design biomaterials as promising diagnostic tools, therapeutic solutions, or tissue …

How microbes read the map: Effects of implant topography on bacterial adhesion and biofilm formation

SW Lee, KS Phillips, H Gu, M Kazemzadeh-Narbat… - Biomaterials, 2021 - Elsevier
Microbes have remarkable capabilities to attach to the surface of implanted medical devices
and form biofilms that adversely impact device function and increase the risk of multidrug …

Implant fibrosis and the underappreciated role of myofibroblasts in the foreign body reaction

N Noskovicova, B Hinz, P Pakshir - Cells, 2021 - mdpi.com
Body implants and implantable medical devices have dramatically improved and prolonged
the life of countless patients. However, our body repair mechanisms have evolved to isolate …

Suppression of the fibrotic encapsulation of silicone implants by inhibiting the mechanical activation of pro-fibrotic TGF-β

N Noskovicova, R Schuster, S van Putten… - Nature Biomedical …, 2021 - nature.com
The fibrotic encapsulation of implants involves the mechanical activation of myofibroblasts
and of pro-fibrotic transforming growth factor beta 1 (TGF-β1). Here, we show that both …

Multifunctional cold spray coatings for biological and biomedical applications: A review

TY Liao, A Biesiekierski, CC Berndt, PC King… - Progress in Surface …, 2022 - Elsevier
A variety of coating techniques are available for medical devices to be tailored with surface
properties aimed at optimizing their performance in biological environments. Cold spray, as …

Antibacterial surface treatment for orthopaedic implants

J Gallo, M Holinka, CS Moucha - International journal of molecular …, 2014 - mdpi.com
It is expected that the projected increased usage of implantable devices in medicine will
result in a natural rise in the number of infections related to these cases. Some patients are …

Progress in niobium oxide-containing coatings for biomedical applications: a critical review

MS Safavi, FC Walsh, L Visai, J Khalil-Allafi - ACS omega, 2022 - ACS Publications
Typically, pure niobium oxide coatings are deposited on metallic substrates, such as
commercially pure Ti, Ti6Al4 V alloys, stainless steels, niobium, TiNb alloy, and Mg alloys …

Regulation of immune response by bioactive ions released from silicate bioceramics for bone regeneration

Y Huang, C Wu, X Zhang, J Chang, K Dai - Acta biomaterialia, 2018 - Elsevier
Silicate bioceramics have been considered to possess a wide prospect of clinical
application for orthopedic tissue regeneration due to their excellent osteogenesis and …

Natural-based biomaterials for peripheral nerve injury repair

BE Fornasari, G Carta, G Gambarotta… - … in bioengineering and …, 2020 - frontiersin.org
Peripheral nerve injury treatment is a relevant problem because of nerve lesion high
incidence and because of unsatisfactory regeneration after severe injuries, thus resulting in …

Advances in multifunctional bioactive coatings for metallic bone implants

MP Nikolova, MD Apostolova - Materials, 2022 - mdpi.com
To fix the bone in orthopedics, it is almost always necessary to use implants. Metals provide
the needed physical and mechanical properties for load-bearing applications. Although …