Postmenopausal women represent an important target population in need of preventative
cardiometabolic approaches. The loss of estrogen following the menopause eliminates …

Estrogen plays a prominent role in regulating and coordinating energy homeostasis
throughout the growth, development, reproduction, and aging of women. Estrogen receptors …

Beta-3 adrenergic receptor activation via exercise or CL316, 243 (CL) induces white
adipose tissue (WAT) browning, improves glucose tolerance, and reduces visceral adiposity …

Estrogen deficiency causes metabolic disorders in humans and rodents, including in part
due to changes in energy expenditure. We have shown previously that skeletal muscle …

Mice are the most commonly used model organism for human biology, and failure to
acknowledge fundamental differences in thermal biology between these species has …

Declining estrogen (E2) leads to physical inactivity and adipose tissue (AT) dysfunction.
Mechanisms are not fully understood, but E2's effects on dopamine (DA) activity in the …

White adipose tissue (WAT) dysfunction independently predicts cardiometabolic disease, yet
there is a lack of effective adipocyte-targeting therapeutics. B3AR agonists enhance …

Growing evidence indicates that estrogen plays a pivotal role in neuroprotection against
cerebral ischemia, but the molecular mechanism of this protection is still elusive. N‐myc …

Estrogen plays an important role in adipose tissue (AT) metabolism. Post-menopausal
estrogen loss leads to increased abdominal fat and worsened metabolic outcomes …

Mice are the most commonly used model organism of human biology, especially for
research into the effects of environmental and pharmacological perturbations such as …