A microbial polyhydroxyalkanoates (PHA) based bio-and materials industry
GQ Chen - Chemical society reviews, 2009 - pubs.rsc.org
Biopolyesters polyhydroxyalkanoates (PHA) produced by many bacteria have been
investigated by microbiologists, molecular biologists, biochemists, chemical engineers …
investigated by microbiologists, molecular biologists, biochemists, chemical engineers …
CNS glucose metabolism in Amyotrophic Lateral Sclerosis: a therapeutic target?
Amyotrophic lateral sclerosis (ALS) is a fatal progressive neurodegenerative disorder
primarily characterized by selective degeneration of both the upper motor neurons in the …
primarily characterized by selective degeneration of both the upper motor neurons in the …
The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies
M Maalouf, JM Rho, MP Mattson - Brain research reviews, 2009 - Elsevier
Both calorie restriction and the ketogenic diet possess broad therapeutic potential in various
clinical settings and in various animal models of neurological disease. Following calorie …
clinical settings and in various animal models of neurological disease. Following calorie …
Water soluble polyhydroxyalkanoates: future materials for therapeutic applications
Polyhydroxyalkanoates (PHAs) are excellent candidate biomaterials due to their exceptional
biodegradability and biocompatibility. However, PHAs need to have tunable hydrophilicity …
biodegradability and biocompatibility. However, PHAs need to have tunable hydrophilicity …
Neuroprotective and disease-modifying effects of the ketogenic diet
M Gasior, MA Rogawski… - Behavioural pharmacology, 2006 - journals.lww.com
The ketogenic diet has been in clinical use for over 80 years, primarily for the symptomatic
treatment of epilepsy. A recent clinical study has raised the possibility that exposure to the …
treatment of epilepsy. A recent clinical study has raised the possibility that exposure to the …
Ketones inhibit mitochondrial production of reactive oxygen species production following glutamate excitotoxicity by increasing NADH oxidation
M Maalouf, PG Sullivan, L Davis, DY Kim, JM Rho - Neuroscience, 2007 - Elsevier
Dietary protocols that increase serum levels of ketones, such as calorie restriction and the
ketogenic diet, offer robust protection against a multitude of acute and chronic neurological …
ketogenic diet, offer robust protection against a multitude of acute and chronic neurological …
Mitochondria, oxidative stress, and temporal lobe epilepsy
S Waldbaum, M Patel - Epilepsy research, 2010 - Elsevier
Mitochondrial oxidative stress and dysfunction are contributing factors to various
neurological disorders. Recently, there has been increasing evidence supporting the …
neurological disorders. Recently, there has been increasing evidence supporting the …
Recent progress and challenges in cyanobacterial autotrophic production of polyhydroxybutyrate (PHB), a bioplastic
M Das, SK Maiti - Journal of Environmental Chemical Engineering, 2021 - Elsevier
Plastic plays a crucial role in the household, industrial, and healthcare sectors and has
become an integral part of human civilization. The non-biodegradable nature of plastic leads …
become an integral part of human civilization. The non-biodegradable nature of plastic leads …
Ketone bodies as a therapeutic for Alzheimer's disease
ST Henderson - Neurotherapeutics, 2008 - Springer
An early feature of Alzheimer's disease (AD) is region-specific declines in brain glucose
metabolism. Unlike other tissues in the body, the brain does not efficiently metabolize fats; …
metabolism. Unlike other tissues in the body, the brain does not efficiently metabolize fats; …
Cerebral metabolic adaptation and ketone metabolism after brain injury
ML Prins - Journal of Cerebral Blood Flow & Metabolism, 2008 - journals.sagepub.com
The developing central nervous system has the capacity to metabolize ketone bodies. It was
once accepted that on weaning, the 'post-weaned/adult'brain was limited solely to glucose …
once accepted that on weaning, the 'post-weaned/adult'brain was limited solely to glucose …