Mesenchymal Stromal Cells (MSC) are key candidates for cellular therapies. Although most
therapeutic applications have focused on adult bone marrow derived MSC, increasing …

There is a growing need for effective animal models to carry out experimental studies on
human hematopoietic and immune systems without putting individuals at risk. Progress in …

Cell-based regenerative medicine is of growing interest in biomedical research. The role of
stem cells in this context is under intense scrutiny and may help to define principles of organ …

Mesenchymal stem cells (MSC) have been isolated from almost every adult tissue. In cord
blood (CB), different non-hematopoietic CD45-, CD34− adherent cell populations can be …

The past 20 years of experience with umbilical cord blood transplantation have
demonstrated that cord blood is effective in the treatment of a spectrum of diseases …

In addition to hematopoietic stem cells, cord blood (CB) also contains different
nonhematopoietic CD45−, CD34− adherent cell populations: cord blood mesenchymal …

Recently, the antagonizing effect on the differentiation of mesenchymal stem cells (MSCs) by
toll‐like receptor (TLR) ligands, was described. Our study shows that on more primitive cord …

Background Bone marrow mesenchymal stem cells support proliferation and differentiation
of hematopoietic progenitor cells in vitro. Since these cells constitute a rare subset of bone …

Umbilical cord blood (UCB) serves as a source of hematopoietic stem and progenitor cells
(HSPCs) utilized in the regeneration of hematopoietic and immune systems, forming a …

For the last 5 years cord blood (CB) has been under intense experimental investigation in in
vitro differentiation models and in preclinical animal models ranging from bone to muscle …