The potential therapeutic use of some Cannabis sativa plant compounds has been attracting
great interest, especially for managing neuropsychiatric disorders due to the relative lack of …

Autophagy is a highly conserved catabolic process that mediates degradation of pernicious
or dysfunctional cellular components, such as invasive pathogens, senescent proteins, and …

Substance use disorder is characterized by repeated use of a substance, leading to
clinically significant distress, making it a serious public health concern. The …

Cocaine abuse continues to be a serious health problem worldwide. Despite intense
research there is currently no FDA-approved medication to treat cocaine use disorder. The …

Learning to associate cues or contexts with potential threats or rewards is adaptive and
enhances survival. Both aversive and appetitive memories are therefore powerful drivers of …

Cannabis sativa (cannabis) is one of the oldest plants cultivated by men. Cannabidiol (CBD)
is the major non-psychomimetic compound derived from cannabis. It has been proposed to …

Beneficial effects of cannabidiol (CBD) have been described for a wide range of psychiatric
disorders, including anxiety, psychosis, and depression. The mechanisms responsible for …

Medicinal use of Cannabis sativa L. has an extensive history and it was essential in the
discovery of phytocannabinoids, including the Cannabis major psychoactive compound—Δ9 …

Neuropsychiatric disorders such as schizophrenia are associated with cognitive impairment,
including learning, memory and attention deficits. Antipsychotic drugs are limited in their …

Drug treatments available for the management of substance use disorders (SUD) present
multiple limitations in efficacy, lack of approved treatments or alarming relapse rates. These …