Bioavailability enhancement techniques for poorly aqueous soluble drugs and therapeutics
The low water solubility of pharmacoactive molecules limits their pharmacological potential,
but the solubility parameter cannot compromise, and so different approaches are employed …
but the solubility parameter cannot compromise, and so different approaches are employed …
Cyclodextrin metal–organic frameworks and derivatives: recent developments and applications
SV Dummert, H Saini, MZ Hussain, K Yadava… - Chemical Society …, 2022 - pubs.rsc.org
While there is a tremendous amount of scientific research on metal organic frameworks
(MOFs) for gas storage/separation, catalysis and energy storage, the development and …
(MOFs) for gas storage/separation, catalysis and energy storage, the development and …
Cyclodextrins: Structural, chemical, and physical properties, and applications
Due to their unique structural, physical and chemical properties, cyclodextrins and their
derivatives have been of great interest to scientists and researchers in both academia and …
derivatives have been of great interest to scientists and researchers in both academia and …
Drug delivery by supramolecular design
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …
Research status of self-healing hydrogel for wound management: A review
A Zhang, Y Liu, D Qin, M Sun, T Wang… - International Journal of …, 2020 - Elsevier
Wound management has attracted significant interest in view of the broad demand market.
Dressings are playing crucial roles in wounds management because they can protect the …
Dressings are playing crucial roles in wounds management because they can protect the …
Cyclodextrin–drug inclusion complexes: In vivo and in vitro approaches
SB Carneiro, FI Costa Duarte, L Heimfarth… - International journal of …, 2019 - mdpi.com
This review aims to provide a critical review of the biological performance of natural and
synthetic substances complexed with cyclodextrins, highlighting:(i) inclusion complexes with …
synthetic substances complexed with cyclodextrins, highlighting:(i) inclusion complexes with …
Biopolymer nano-particles and natural nano-carriers for nano-encapsulation of phenolic compounds
AF Esfanjani, SM Jafari - Colloids and Surfaces B: Biointerfaces, 2016 - Elsevier
Phenolic compounds are major micronutrients in our diet, 1 and evidence for their role in the
prevention of degenerative diseases such as cancer, inflammation and neurodegenerative …
prevention of degenerative diseases such as cancer, inflammation and neurodegenerative …
[HTML][HTML] Biomedical applications of supramolecular systems based on host–guest interactions
X Ma, Y Zhao - Chemical reviews, 2015 - ACS Publications
The development of supramolecular chemistry dates back to 1987 when Lehn, Cram, and
Pedersen won the Nobel Prize on account of their leading discoveries in the host–guest …
Pedersen won the Nobel Prize on account of their leading discoveries in the host–guest …
Polymorph impact on the bioavailability and stability of poorly soluble drugs
R Censi, P Di Martino - Molecules, 2015 - mdpi.com
Drugs with low water solubility are predisposed to poor and variable oral bioavailability and,
therefore, to variability in clinical response, that might be overcome through an appropriate …
therefore, to variability in clinical response, that might be overcome through an appropriate …
A comprehensive review on cyclodextrin‐based carriers for delivery of chemotherapeutic cytotoxic anticancer drugs
B Gidwani, A Vyas - BioMed research international, 2015 - Wiley Online Library
Most of the cytotoxic chemotherapeutic agents have poor aqueous solubility. These
molecules are associated with poor physicochemical and biopharmaceutical properties …
molecules are associated with poor physicochemical and biopharmaceutical properties …